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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > STRESTMARQ/抗HSP70B(植物)抗体/SPC-315D/100-µl
商品详细STRESTMARQ/抗HSP70B(植物)抗体/SPC-315D/100-µl
STRESTMARQ/抗HSP70B(植物)抗体/SPC-315D/100-µl
STRESTMARQ/抗HSP70B(植物)抗体/SPC-315D/100-µl
商品编号: SPC-315D
市场价: ¥6160.00
美元价: 3696.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameHSP70B(Plant)Antibody
Description

RabbitAnti-AlgaeHSP70B(Plant)Polyclonal

SpeciesReactivityAlgae,Algae(Chlamydomonasreinhardtii),Algae(Desmodesmussubspicatus),Moss(Physcomitrellapatens),Plant
ApplicationsWB,IP
AntibodyDilutionWB(1:10000);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesAlgae
ImmunogenMatureHSP70BproteinexpressedwithN-andC-terminalhexahistidinetagsinE.coli,purifiedwithNi-NTA
ConjugatesUnconjugated

Properties

StorageBufferLyophilizedrabbitAntiserum.Forreconstitutionadd100µlofsterilewater.
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationRabbitantiserum
ClonalityPolyclonal
SpecificityDetects~70kDa.
CiteThisProductStressMarqBiosciencesCat#SPC-315,RRID:AB_1501401

BIOLOGicalDescription

AlternativeNamesHSP701Antibody,HSP702Antibody,HSP70.1Antibody,HSP72Antibody,HSPA1Antibody,HSPA1AAntibody,HSPA1BAntibody
ResearchAreasCancer,HeatShock
CellularLocalizationCytoplasm
AccessionNumberXP_001696432.1
GeneID5722220
SwissProtA8HYV3
ScientificBackgroundHSP70B(heatshockprotein70B)isanuclear-encoded,chloroplast-targetedchaperoneoftheHSP70family.ItisthemajorHSP70inthestromaofChlamydomonaschloroplasts.ItinteractswithHSP90C,CGE1,CDJ2andVIPP1(1-3).IthasbeenshownthatusingChlamydomonasreinhardtiiasplantmodelorganismthealgaencodesaHEPhomolog(termedHEP2)thatislocalizedtothestroma(4).HEP2isexpressedconstitutivelyasalowabundanceproteinwithanapparentmolecularmassof~21kDa.IncellextractsHEP2interactswithHSP70BinanATP-dependentfashion.CoexpressionofHSP70BwithHEP2inE.coliyieldshighlevelsofCGE1-bindingcompetentHSP70B,whichalsodisplayedATPaseactivity(4).InactiveHSP70BwasmorepronetoproteolysisthanactiveHSP70B.AlthoughinactiveHSP70BinteractswithHEP2,itisnotactivated.ActiveHSP70Bremainsactivefor48hintheabsenceofHEP2,suggestingthatHEP2wasnotinvolvedinmaintainingHSP70Binanactivestate.However,itwasfoundthatsomeHSP70BexpressedasafusionproteinwithanN-terminalextensionwasactivatedwhenHEP2waspresentduringcleavageofthefusionprotein,suggestingthatinvivoHEP2mightberequiredforrenewedfoldingofHSP70Baftertransitpeptidecleavage(4).LookingformoreinformationonHSP70?VisitournewHSP70ScientificResourceGuideathttp://www.HSP70.com.
References1.SchrodaM.,VallonO.,WollmanF.A.andBeckC.F.(1999)PlantCell.11:1165-1178.
2.SchrodaM.,etal.(2001)PlantCell.13:2823-2839.
3.LiuC.,etal.(2005)MolBiolCell.16:1165-1177.
4.WillundF.,etal.(2008)J.Biol.Chem.,283(24):16363-16373.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。