StressMarq/Herbimycin A/SIH-116A/100-µg
商品编号：
SIH-116A
市场价：
¥2980.00
美元价：
1788.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | HerbimycinA |
| Description | Hsp90inhibitor |
| Purity | >98% |
| CASNo. | 70563-58-5 |
| MolecularFormula | C30H42N2O10,C30H42N2O9 |
| MolecularWeight | 574.3,575.3 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(>25mg/ml)andethanol(10mg/ml) |
| Source | Synthetic |
| Appearance | YellowSolid |
| SMILES | C[[email protected]]1C[[email protected]@H]([[email protected]@H]([[email protected]](/C=C(/[[email protected]@H]([[email protected]](/C=CC=C(C(=O)NC2=CC(=O)C=C([[email protected]@H]1OC)C2=O)/C)OC)OC(=O)N)C)C)OC)OC |
| InChI | InChI=1S/C30H42N2O9/c1-16-10-9-11-23(37-5)28(41-30(31)36)18(3)12-17(2)27(40-8)24(38-6)13-19(4)26(39-7)21-14-20(33)15-22(25(21)34)32-29( |
| InChIKey | MCAHMSDENAOJFZ-BVXDHVRPSA-N |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection |
| CiteThisProduct | HerbimycinA(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-116) |
BIOLOGicalDescription
| AlternativeNames | [(2R,3S,5S,6R,7S,8E,10S,11S,12E,14E)-2,5,6,11-tetramethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azABIcyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl]carbamate |
| ResearchAreas | Cancer,HeatShock |
| PubChemID | 6436247 |
| ScientificBackground | HerbimycinA,abenzoquinoidansamycinantibiotic,irreversIBLyandselectivelyinhibitstyrosinekinasesbyreactingwiththiolgroups(1,2).ItiseffectiveonSrc,Yes,Fps,Ros,AblandErbBoncogeneproducts(1-3)andinhibitsthrombin-inducedtyrosinephosphorylationofphospholipaseC(4).LookingformoreinformationonHSP90?VisitournewHSP90ScientificResourceGuideathttp://www.HSP90.ca. |
| References | 1.UeharaY.,andFukazawaH.(1991)MethodsEnzymol.201:370. 2.FukazawaH.,etal.(1991)Biochem.Pharmacol.42:1661. 3.SatohT.,etal.(1992)J.Biol.Chem.267:2537. 4.WeissR.,andNuccitelliR.(1992)J.Biol.Chem.267:5608. |
ProductImages
ChemicalstructureofHerbimycinA(SIH-116),aHsp90inhibitor.CAS#:70563-58-5.MolecularFormula:C30H42N2O9.MolecularWeight:574.3g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
