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当前位置： 首页 > 产品中心 > acid_base_buffer_solution > STRESTMARQ/抗HDAC1抗体/SPC-1324D-A390/100-微升
商品详细STRESTMARQ/抗HDAC1抗体/SPC-1324D-A390/100-微升
STRESTMARQ/抗HDAC1抗体/SPC-1324D-A390/100-微升
STRESTMARQ/抗HDAC1抗体/SPC-1324D-A390/100-微升
商品编号： SPC-1324D-A390
市场价： ¥6060.00
美元价： 3636.00
产地： 美国(厂家直采)
公司：
产品分类： 酸碱缓冲液
公司分类： acid_base_buffer_solution
联系Q Q： 3392242852
电话号码： 4000-520-616
电子邮箱： info@ebiomall.com
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商品介绍

Overview:

Product Name HDAC1 Antibody
Description

Rabbit Anti-Human HDAC1 Polyclonal

Species Reactivity Human, Mouse, Rat
Applications WB, IHC, ICC/IF, ELISA
Antibody Dilution WB (1:1000), IHC (1:100), ICC/IF (1:500), ELISA (1:10000); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen Synthesized peptide derived from human HDAC1.
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Affinity Purified
Clonality Polyclonal
Isotype IgG
Specificity Detects endogenous levels of total HDAC1 protein.
Cite This Product StressMarq Biosciences Cat# SPC-1324, RRID: AB_2713619
Certificate of Analysis A 1:1000 dilution of SPC-1324 was sufficient for detection of HDAC1 in 10 µg of NIH/3T3 cell lysates by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names DKFZp686H12203 antibody, GON 10 antibody, HD1 antibody, HDAC 1 antibody, HDAC1 antibody, HDAC1_HUMAN antibody, Histone deacetylase 1 antibody, Reduced potassium dependency yeast homolog like 1 antibody, RPD3 antibody, RPD3L1 antibody
Cellular Localization Nucleus
Accession Number NP_004955.2
Gene ID 3065
Swiss Prot Q13547
Scientific Background Histone deacetylase 1 is an enzyme that in humans is encoded by the HDAC1 gene. Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
References 1. Taunton J. et al. (1996) Science 272 (5260): 408–11.
2. Gerdin AK. (2010) Acta Ophthalmologica 88 (S248).

Product Images

<p>Immunohistochemistry analysis using Rabbit Anti-HDAC1 Polyclonal Antibody (SPC-1324). Tissue: Lung Carcinoma Tissue. Species: Human. Primary Antibody: Rabbit Anti-HDAC1 Polyclonal Antibody (SPC-1324) at 1:100. The image on the right is treated with the synthesized peptide.</p>

Immunohistochemistry analysis using Rabbit Anti-HDAC1 Polyclonal Antibody (SPC-1324). Tissue: Lung Carcinoma Tissue. Species: Human. Primary Antibody: Rabbit Anti-HDAC1 Polyclonal Antibody (SPC-1324) at 1:100. The image on the right is treated with the synthesized peptide.

<p>Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-HDAC1 Polyclonal Antibody (SPC-1324). Tissue: NIH/3T3. Species: Mouse. Primary Antibody: Rabbit Anti-HDAC1 Polyclonal Antibody (SPC-1324) at 1:100. The image on the right is treated with the synthesized peptide.</p>

Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-HDAC1 Polyclonal Antibody (SPC-1324). Tissue: NIH/3T3. Species: Mouse. Primary Antibody: Rabbit Anti-HDAC1 Polyclonal Antibody (SPC-1324) at 1:100. The image on the right is treated with the synthesized peptide.

<p>Western blot analysis of Mouse NIH/3T3 cell lysates showing detection of ~62kDa HDAC1 protein using Rabbit Anti-HDAC1 Polyclonal Antibody (SPC-1324). Lane 1: Mouse NIH/3T3. Lane 2: Mouse NIH/3T3 treated with the immunizing peptide. Primary Antibody: Rabbit Anti-HDAC1 Polyclonal Antibody (SPC-1324) at 1:1000. Predicted/Observed Size: ~62kDa.</p>

Western blot analysis of Mouse NIH/3T3 cell lysates showing detection of ~62kDa HDAC1 protein using Rabbit Anti-HDAC1 Polyclonal Antibody (SPC-1324). Lane 1: Mouse NIH/3T3. Lane 2: Mouse NIH/3T3 treated with the immunizing peptide. Primary Antibody: Rabbit Anti-HDAC1 Polyclonal Antibody (SPC-1324) at 1:1000. Predicted/Observed Size: ~62kDa.

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  ATTO 390
Overview:

  • High fluorescence yield
  • Large Stokes-shift (89 nm)
  • Good photostability
  • Moderately hydrophilic
  • Good solubility in polar solvents
  • Coumarin derivate, uncharged
  • Low molar mass: 343.42 g/mol 

ATTO 390 Datasheet

ATTO 390 Fluorescent Dye Excitation and Emission SpectraOptical Properties:

λex = 390 nm

λem = 479 nm

εmax = 2.4×104

Φf = 0.90

τfl = 5.0 ns

Brightness = 21.6

Laser = 365 or 405 nm

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
公司介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒
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