StressMarq/H89 Dihydrochloride/SIH-452-25MG/25-mg
商品编号：
SIH-452-25MG
市场价：
¥6800.00
美元价：
4080.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | H89Dihydrochloride |
| Description | PKAinhibitor |
| Purity | 99%(TLC) |
| CASNo. | 127243-85-0 |
| MolecularFormula | C20H22BrCl2N3O2S |
| MolecularWeight | 519.3 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(25mg/ml),methanoland50%ethanol/water(20mg/ml) |
| Source | Synthetic |
| Appearance | Whitetooff-whitesolid |
| SMILES | C1=C(C2=C(C=C1)C=NC=C2)[S](NCCNCC=CC3=CC=C(Br)C=C3)(=O)=O |
| InChI | InChI=1S/C20H20BrN3O2S/c21-18-8-6-16(7-9-18)3-2-11-22-13-14-24-27(25,26)20-5-1-4-17-15-23-12-10-19(17)20/h1-10,12,15,22,24H,11,13-14H2/b3-2+ |
| InChIKey | ZKZXNDJNWUTGDK-NSCUHMNNSA-N |
| SafetyPhrases | Classification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection. |
| CiteThisProduct | H89Dihydrochloride(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-452) |
BIOLOGicalDescription
| AlternativeNames | N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide.2HCl |
| ResearchAreas | CellSignaling |
| PubChemID | 449241 |
| ScientificBackground | H89DihydrochlorideisapotentandselectiveinhibitorofcAMP-dependentproteinkinase(PKA).IthasalsobeenshowntoinhibitCaMkinaseII,caseinkinaseIandMYLK,aswellas,Rsk-2,MSK1,Akt1,PKCµ,Rock-2,p70S6kinaseα.H89Dihydrochloridecaninduceapoptosis.Itiscellpermeable. |
| References | 1.Bouschet,T.,(2003)J.Biol.Chem.278(7):4778–4785. 2.FindikD.,SongQ.,HidakaH.,&LavinM.(1995)J.Cell.Biochem.57(1):12–21. 3.DaviesS.P.,ReddyH.,CaivanoM.,&CohenP.(2000)Biochem.J.351(Pt1):95–105. |
ProductImages
ChemicalstructureofH89Dihydrochloride(SIH-452),aPKAinhibitor.CAS#:127243-85-0.MolecularFormula:C20H22BrCl2N3O2S.MolecularWeight:519.3g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
