StressMarq/GW 441756/SIH-450-50MG/50-mg
商品编号：
SIH-450-50MG
市场价：
¥11900.00
美元价：
7140.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | GW441756 |
| Description | NGFRkinaseinhibitor |
| Purity | >99% |
| CASNo. | 504433-23-2 |
| MolecularFormula | C17H13N3O |
| MolecularWeight | 275.3 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto15mMinDMSO |
| Source | Synthetic |
| Appearance | Redsolid |
| SMILES | CN1C=C(C2=CC=CC=C21)/C=C3/C4=C(C=CC=N4)NC3=O |
| InChI | InChI=1S/C17H13N3O/c1-20-10-11(12-5-2-3-7-15(12)20)9-13-16-14(19-17(13)21)6-4-8-18-16/h2-10H,1H3,(H,19,21)/b13-9- |
| InChIKey | NXNQLECPAXXYTR-LCYFTJDESA-N |
| SafetyPhrases | Classification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection. |
| CiteThisProduct | GW441756(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-450) |
BIOLOGicalDescription
| AlternativeNames | 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 9943465 |
| ScientificBackground | GW441756isapotentandselectiveNGFreceptortyrosinekinaseA(TrkA)inhibitor.Specifically,itisshowntoblockapoptosisandcelldeathinducedbyTrkA.GW-441756displays>100-foldselectivityoverarangeofotherkinases. |
| References | 1.WoodE.R.,etal.(2004)Bioorganic&Med.Chem.Ltr.14(4):953–957. 2.JungE.J.,KimC.W.,&KimD.R.(2008)Exp.Mol.Med.40(3):276–285. |
ProductImages
ChemicalstructureofGW441756(SIH-450),aNGFRkinaseinhibitor.CAS#:504433-23-2.MolecularFormula:C17H13N3O.MolecularWeight:275.3g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
