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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-GUK1 Antibody (pTyr53)/SPC-992D-PCP/100-µl
商品详细StressMarq/Anti-GUK1 Antibody (pTyr53)/SPC-992D-PCP/100-µl
StressMarq/Anti-GUK1 Antibody (pTyr53)/SPC-992D-PCP/100-µl
StressMarq/Anti-GUK1 Antibody (pTyr53)/SPC-992D-PCP/100-µl
商品编号: SPC-992D-PCP
市场价: ¥6820.00
美元价: 4092.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name GUK1 Antibody (pTyr53)
Description

Rabbit Anti-Human GUK1 (pTyr53) Polyclonal

Species Reactivity Human
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A phospho-specific peptide corresponding to residues surrounding Tyr53 of human GUK1 (AA50-56)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 21.726 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-992, RRID: AB_2708255
Certificate of Analysis A 1:250 dilution of SPC-992 was sufficient for detection of GUK1 (pTyr53) in 10 µg of human kidney lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names GMK Antibody, GMP kinase Antibody, Guanylate kinase Antibody, GUK1 Antibody, KGUA_HUMAN Antibody
Cellular Localization Cytosol
Accession Number NP_000849
Gene ID 2987
Swiss Prot Q16774
Scientific Background GUK1 (guanylate kinase 1), also known as GMK (GMP kinase), is a 197 amino acid protein that contains one guanylate kinase-like domain and belongs to the guanylate kinase family. Ubiquitously expressed, GUK1 exists as a monomer that catalyzes the ATP-dependent conversion of GMP to GDP, thereby playing an essential role in the recycling of GMP. Via its catalytic activity, GUK1 is thought to participate in regulating the supply of guanine nucleotides to signal transduction pathways. Overexpression of GUK1 is associated with pituitary adenocarcinomas, suggesting that GUK1 is involved in tumorigenesis.

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 PerCP 
Overview:

  • Peridinin-Chlorophyll-Protein Complex
  • Small phycobiliprotein
  • Isolated from red algae
  • Large stokes shift (195 nm)
  • Molecular Weight: 35 kDa

PerCP Datasheet

 PerCP Fluorophore Absorption and Emission SpectrumOptical Properties:

λex = 482 nm

λem = 677 nm

εmax = 1.96 x 106

Laser = 488 nm

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。