StressMarq/GSK690693 Hydrochloride/SIH-448-5MG/5-mg
商品编号：
SIH-448-5MG
市场价：
¥2300.00
美元价：
1380.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | GSK690693Hydrochloride |
| Description | AKTkinaseinhibitor |
| Purity | >98%(HPLC) |
| CASNo. | 937174-76-0 |
| MolecularFormula | C21H27N7O3 |
| MolecularWeight | 425.5 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto50mMinDMSO |
| Source | Synthetic |
| Appearance | Whitetobeigesolid |
| SMILES | CCN1C2=C(C(=NC=C2OC[[email protected]]3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N |
| InChI | InChI=1S/C21H27N7O3/c1-4-28-18-15(30-12-13-6-5-9-23-10-13)11-24-14(7-8-21(2,3)29)16(18)25-20(28)17-19(22)27-31-26-17/h11,13,23,29H,4-6,9-10,12H2,1-3H3,(H2,22,27)/t13-/m0/s1 |
| InChIKey | KGPGFQWBCSZGEL-ZDUSSCGKSA-N |
| SafetyPhrases | Classification:Acutetoxicity,Oral(Category3)SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H301Toxicifswallowed.Precautionarystatements:P301+P310IFSWALLOWED:ImmediatelycallaPOISONCENTERordoctor/physician. |
| CiteThisProduct | GSK690693Hydrochloride(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-448) |
BIOLOGicalDescription
| AlternativeNames | 4-[2-(4-Amino-1,2,5-oxADIazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 16725726 |
| ScientificBackground | GSK690693HydrochlorideisanATP-competitivepan-Aktkinaseinhibitor.Itisderivedfromaminofurazan.Ithasshowntoproduceantiproliferativeandapoptoticeffectsintumorcelllines. |
| References | 1.HeerdingD.A.,etal.(2008)J.Med.Chem.51(18):5663–5679. 2.RhodesN.,etal.(2008)CancerRes.68(7):2366–2374. |
ProductImages
ChemicalstructureofGSK690693Hydrochloride(SIH-448),aAKTkinaseinhibitor.CAS#:937174-76-0.MolecularFormula:C21H27N7O3.MolecularWeight:425.5g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
