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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-GRK2 Antibody (pTyr356)/SPC-922D/100-µl
商品详细StressMarq/Anti-GRK2 Antibody (pTyr356)/SPC-922D/100-µl
StressMarq/Anti-GRK2 Antibody (pTyr356)/SPC-922D/100-µl
StressMarq/Anti-GRK2 Antibody (pTyr356)/SPC-922D/100-µl
商品编号: SPC-922D
市场价: ¥5900.00
美元价: 3540.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name GRK2 Antibody (pTyr356)
Description

Rabbit Anti-Human GRK2 (pTyr356) Polyclonal

Species Reactivity Human
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A phospho-specific peptide corresponding to residues surrounding Tyr356 of human GRK2 (AA353-359)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 79.574 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-922, RRID: AB_2706995
Certificate of Analysis A 1:250 dilution of SPC-922 was sufficient for detection of GRK2 (pTyr356) in 10 µg of human colon cancer cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names ADRBK1 Antibody, Adrenergic beta receptor kinase 1 Antibody, ARBK1_HUMAN Antibody, BARK Antibody, BARK1 Antibody, Beta adrenergic receptor kinase 1 Antibody, Beta ARK 1 Antibody, G protein coupled receptor kinase 2 Antibody
Research Areas Cell Signaling, Neuroscience, Neurotransmitter Receptors
Cellular Localization Cytoplasm, Cell membrane
Accession Number NP_001610
Gene ID 156
Swiss Prot P25098
Scientific Background G protein-coupled receptor kinases (GRKs) belong to a class of enzymes that regulate signal transduction. At least seven members of the GRK family have been identified. These include rhodopsin kinase (GRK 1), two forms of beta-adrenergic receptor kinase: GRK 2 (betaARK, betaARK1) and GRK 3 (betaARK2), IT-11 (GRK 4), GRK 5, GRK 6 and GRK 7. Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。