StressMarq/Genistein/SIH-446-10MG/10-mg
商品编号：
SIH-446-10MG
市场价：
¥600.00
美元价：
360.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | GeNISTein |
| Description | Tyrosinekinaseinhibitor |
| Purity | >98%(HPLC) |
| CASNo. | 446-72-0 |
| MolecularFormula | C15H10O5 |
| MolecularWeight | 270.2 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(30mg/ml),100%ethanol(4mg/ml)ordiluteaqueousbase;insolubleinwater |
| Source | Synthetic |
| Appearance | Creamyoff-whitesolid |
| SMILES | C1=C(O)C=C(C2=C1OC=C(C2=O)C3=CC=C(O)C=C3)O |
| InChI | InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H |
| InChIKey | TZBJGXHYKVUXJN-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Acutetoxicity,Oral(Category4),H302SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H302HarmfulifswallowedPrecautionarystatements:P264Washskinthoroughlyafterhandling.P270Donoteat,drinkorsmokewhenusingthisproduct.P301+P312IFSWALLOWED:CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P330Rinsemouth.P501Disposeofcontents/containertoanapprovedwastedisposalplant. |
| CiteThisProduct | Genistein(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-446) |
BIOLOGicalDescription
| AlternativeNames | 4",5,7-Trihydroxyisoflavone,5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one,4′,5,7-Trihydroxyisoflavone,5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 5280961 |
| ScientificBackground | Genisteinhasawiderangeofbiologicalactions.Itisaninhibitoroftyrosineproteinkinase,includingepidermalgrowthfactorreceptorkinase.ItalsoinhibitsDNAtopoisomeraseandα-glucosidase.Itproducescellcyclearrestandapoptosis,andinhibitsendocytosis,aswellas,inhibitsinsulin-inducedglucoseuptakeinADIpocytes. |
| References | 1.AkiyamaT.,etal.(1987)JBiol.Chem.262(12):5592–5595. 2.BazuineM.,vandenBroekP.J.A.,&MaassenJ.A.(2005)Biochem.Biophys.Res.Comm.326(2):511–514. 3.LinassierC.,PierreM.,LePecqJ.B.,&PierreJ.(1990)Biochem.Pharm.39(1):187–193. 4.DeanN.M.,KanemitsuM.,&BoyntonA.L.(1989)Biochem.Biophys.Res.Comm.165(2):795–801. |
ProductImages
ChemicalstructureofGenistein(SIH-446),aTyrosinekinaseinhibitor.CAS#:446-72-0.MolecularFormula:C15H10O5.MolecularWeight:270.2g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
