StressMarq/Anti-FOXP3 antibody/SPC-1323D-FITC/100-µl-免疫在线蚂蚁淘旗下平台

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商品详细StressMarq/Anti-FOXP3 antibody/SPC-1323D-FITC/100-µl

StressMarq/Anti-FOXP3 antibody/SPC-1323D-FITC/100-µl

商品编号： SPC-1323D-FITC

品牌： StressMarq Biosciences

市场价： ¥5880.00

美元价： 3528.00

产地：美国(厂家直采)

公司：

产品分类：酸碱缓冲液

公司分类： acid_base_buffer_solution

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Overview:

Product Name FOXP3 antibody

Description

Rabbit Anti-Human FOXP3 Polyclonal

Species Reactivity Human

Applications WB, IHC, ICC/IF, IP

Antibody Dilution WB (1:2000), IHC (1:200), ICC/IF (1:500); optimal dilutions for assays should be determined by the user.

Host Species Rabbit

Immunogen Species Human

Immunogen A synthesized peptide derived from human FOXP3

Conjugates

Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer	PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Storage Temperature	-20ºC
Shipping Temperature	Blue Ice or 4ºC
Purification	Affinity Purified
Clonality	Polyclonal
Isotype	IgG
Specificity	Detects endogenous levels of total FOXP3
Cite This Product	StressMarq Biosciences Cat# SPC-1323, RRID: AB_2713601
Certificate of Analysis	A 1:1000 dilution of SPC-1323 was sufficient for detection of FOXP3 in 10 µg of Jurkat cell lysates by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names	AIID antibody, DIETER antibody, Forkhead box P3 antibody, Forkhead box protein P3 antibody, FOXP3 antibody, FOXP3_HUMAN antibody, FOXP3delta7 antibody, Immune dysregulation polyendocrinopathy enteropathy X linked antibody, Immunodeficiency polyendocrinopathy enteropathy X linked antibody, IPEX antibody, JM2 antibody, MGC141961 antibody, MGC141963 antibody, OTTHUMP00000025832 antibody, OTTHUMP00000025833 antibody, OTTHUMP00000226737 antibody, PIDX antibody, Scurfin antibody, XPID antibody
Cellular Localization	Cytoplasm, Nucleus
Accession Number	NP_054728.2
Gene ID	50943
Swiss Prot	Q9BZS1
Scientific Background	FOXP3 (forkhead box P3), also known as scurfin, is a protein involved in immune system responses. A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of regulatory T cells. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
References	1. Brunkow ME. et al. (2001) Nature Genetics 27 (1): 68–73. 2. Hori S. et al. (2003) Science 299 (5609): 1057–61. 3. Fontenot JD. et al. (2003) Nature Immunology 4 (4): 330–6. 4. Fontenot JD. et al. (2005) Immunity 22 (3): 329–41.

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FITC (Fluorescein)

Overview:

Excellent fluorescence quantum yield
High rate of photobleaching
Good solubility in water
Broad emission spectrum
pH dependent spectra
Molecular formula: C₂₀H₁₂O₅
Molar mass: 332.3 g/mol

FITC-Fluorescent-conjugate

FITC Fluorescein Fluorophore Excitation and Emission Spectra

Optical Properties:

λ_ex = 494 nm

λ_em = 520 nm

ε_max = 7.3×10⁴

Φ_f = 0.92

τ_fl = 5.0 ns

Brightness = 67.2

Laser = 488 nm

Filter set = FITC

品牌介绍

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。

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