StressMarq/FK506/SIH-214-10MG/10-mg
商品编号：
SIH-214-10MG
市场价：
¥1700.00
美元价：
1020.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | FK506 |
| Description | FKBPinhibitor |
| Purity | >98% |
| CASNo. | 109581-93-3 |
| MolecularFormula | C44H69NO12·H2O |
| MolecularWeight | 804.02 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto100mMinethanol,andto100mMinDMSO |
| Source | Synthetic |
| Appearance | WhiteSolid |
| SMILES | CCC(C)(C)C(=O)C(=O)N1CCCC1C(=O)OCCCC2=CN=CC=C2 |
| InChI | InChI=1S/C44H69NO12/c1-10-13-31-19-25(2)18-26(3)20-37(54-8)40-38(55-9)22-28(5)44(52,57-40)41(49)42(50)45-17-12-11-14-32(45)4 |
| InChIKey | QJJXYPPXXYFBGM-LFZNUXCKSA-N |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionHazardPhrases:H301PrecautionaryPhrases:P301+P310 |
| CiteThisProduct | FK506(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-214) |
BIOLOGicalDescription
| AlternativeNames | 3-(3-Pyridinyl)propyl1-(3,3-dimethyl-2-oxopentanoyl)prolinate,Tacrolimus,Fujimycin |
| ResearchAreas | Cancer,Apoptosis |
| PubChemID | 445643 |
| ScientificBackground | FK506orFujimycinorTacrolimus,isanimmunosuppressant.Itismainlyusedafterallogeneicorgantransplants,butcanalsobeusedtopicallyinthetreatmentofeczema,uveitisandvitiligo(1).ItisamacrolidethatpreventsthedephosphorylationofNF-AT.Itreducespeptidyl-prolylisomeraseactivitybybindingtoFKBP12creatinganewcomplexthatinteractswithandinhibitscalcineurin(2,3). |
| References | 1.NanetteB.,etal.(2004)JAmAcadDerm.51(5):760-766. 2.GanongW.F.,ReviewofMedicalPhysiology(22nded.)LangeMedicalBooks.P.530 3.LiuJ.LaneW.,FriedmanJ,WeissmanIandSchreiberS.(1991)Cell.66(4):807-815 |
ProductImages
ChemicalstructureofFK506(SIH-214),aFKBPinhibitor.CAS#:109581-93-3.MolecularFormula:C44H69NO12·H2O.MolecularWeight:804.02g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
