25-mg-siq/25-mg-siq
商品编号:
SIH-525-25MG
市场价:
¥3920.00
美元价:
2352.00
产品分类:
酸碱缓冲液
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Overview:
ProductName | Ferrostatin-1 |
Description | FerroptosisInhibitor |
Purity | >98%(TLC);NMR(Conforms) |
CASNo. | 347174-05-4 |
MolecularFormula | C15H22N2O2 |
MolecularWeight | 262.4 |
Properties
StorageTemperature | -20ºC |
ShippingTemperature | ShippedAmbient |
ProductType | Inhibitor |
Solubility | SolubleinDMSO(100mg/ml)orethanol(100mg/ml) |
Source | Synthetic |
Appearance | Tanpowder |
SMILES | CCOC(=O)c1ccc(c(c1)N)NC2CCCCC2 |
SafetyPhrases | Classification:Skinirritation(Category2),H315SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H315Causesskinirritation.H319Causesseriouseyeirritation.Precautionarystatements:P260Donotbreathedust/fume/gas/mist/vapours/sprayP264Washskinthoroughlyafterhandling.P280Wearprotectivegloves.P302+P352IFONSKIN:Washwithplentyofsoapandwater.P304+340IfINHALED:RemovevictimtofreshairandkeepatrestinapositioncomfortableforbreathingP305+351++338IFINEYES:Rinsecontinuouslywithwaterforseveralminutes.Removecontactlensesifpresentandeasytodoso-continuerinsing.P333+313Ifskinirritationorarashoccurs:Getmedicaladvice/attention |
CiteThisProduct | Ferrostatin-1(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-525) |
BIOLOGicalDescription
AlternativeNames | Ethyl3-amino-4-(cyclohexylamino)benzoate |
ResearchAreas | Cancer,Apoptosis,CellSignaling,Neuroscience |
ScientificBackground | Ferrostatin-1inhibitsferroptosis(EC50=60nM),aniron-dependentformofnonapoptoticcelldeath.Itisespeciallypotentofferroptosisincancercellsandglutamate-inducedcelldeathinorganotypicratbrainslices(1).Italsoblocksthecytotoxiceffectsofsorafenibinhepatocellularcarcinomacells(2),andinhibitsoxidativelipiddamageandcelldeathindiversediseasemodels(3). |
References | 1.DixonS.J.,etal.(2012)Cell.149:1060. 2.LouandreC.,etal.(2013)Int.J.Cancer.133:1732. 3.SkoutaR.,etal.(2014)J.Am.Chem.Soc.136:4551. |
ProductImages
ChemicalstructureofFerrostatin-1(SIH-525),aFerroptosisInhibitor.CAS#:347174-05-4.MolecularFormula:C15H22N2O2.MolecularWeight:262.4g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。