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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Felodipine/SIH-323-50MG/50-mg
商品详细StressMarq/Felodipine/SIH-323-50MG/50-mg
StressMarq/Felodipine/SIH-323-50MG/50-mg
StressMarq/Felodipine/SIH-323-50MG/50-mg
商品编号: SIH-323-50MG
市场价: ¥4100.00
美元价: 2460.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameFelodipine
Description

L-typeCachannelblocker

Purity>98%(TLC);NMR(Conforms)
CASNo.72509-76-3
MolecularFormulaC18H19Cl2NO4
MolecularWeight384.25

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleto100mMinethanolandto100mMinDMSO
SourceSynthetic
AppearanceLightYellowSolid
SMILESCCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C
InChIInChI=1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3
InChIKeyRZTAMFZIAATZDJ-UHFFFAOYSA-N
SafetyPhrasesClassification:Harmful.Maybeharmfulifinhaled,swallowedorabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-AvoidcontactwithshinandeyesRiskPhrases:R20/21/22-Harmfulbyinhilation,incontactwithskinandifswallowedR62-PossIBLeriskofimpairedfertilityHazardPhrases:H302
CiteThisProductFelodipine(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-323)

BIOLOGicalDescription

AlternativeNamesEthylmethyl4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate,Plendil
ResearchAreasCalciumChannels,IonChannels,Neuroscience,Voltage-GatedCalciumChannels
PubChemID3333
ScientificBackgroundFelodipineisanL-typeCa2+channelblocker(1).Inisolatedratventricularmyocytes,usingawhole-cellpatch-clamptechnique,itdisplaysaKiof11nM(2).Itisaclinicallyusefulantihypertensiveagent(3)whichattenuatesthehypertrophiceffectofcyclosporineontransplantedhearts(4).
References1.FurakawaT.,etal.(2005)JCardiovasc.Pharmacol.45(3):241-246.
2.ZahradnikovaZ.,MinarovicI.,ZahradnikI.(2007)JPharmacolExp.Ther.322(2):638-645.
3.ManzoB.A.,MatalkaM.S.,RavnanS.L.(2003)Pharmacotherapy.23(11):1508-1512.
4.SchwitterJ.,etal.(1999)JHeartLungTransplant.18(10):1003-1013.

ProductImages

<p>Chemical structure of Felodipine (SIH-323), a L-type Ca channel blocker. CAS #: 72509-76-3. Molecular Formula: C18H19Cl2NO4. Molecular Weight: 384.25 g/mol.</p>

ChemicalstructureofFelodipine(SIH-323),aL-typeCachannelblocker.CAS#:72509-76-3.MolecularFormula:C18H19Cl2NO4.MolecularWeight:384.25g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。