StressMarq/Fasudil/SIH-371-10MG/10MG
商品编号：
SIH-371-10MG
市场价：
¥2240.00
美元价：
1344.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Fasudil |
| Description | ROCKinhibitor |
| Purity | >98%(TLC);NMR(Conforms) |
| CASNo. | 103745-39-7 |
| MolecularFormula | C14H17N3O2S•HCl |
| MolecularWeight | 327.83 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | MaybedissolvedinDMSO(75mg/ml)orwater(100mg/ml) |
| Source | Synthetic |
| Appearance | Powder |
| SMILES | C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3 |
| InChI | InChI=1S/C14H17N3O2S/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14/h1,3-5,7,11,15H,2,6,8-10H2 |
| InChIKey | NGOGFTYYXHNFQH-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-Donotbreathedust.S24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection |
| CiteThisProduct | Fasudil(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-371) |
BIOLOGicalDescription
| AlternativeNames | 1-(5-Isoquinolinylsulfonyl)homopiperazinehydrochloride;5-(1,4-Diazepan-1-ylsulfonyl)isoquinoline |
| ResearchAreas | CellSignaling,Neuroscience |
| PubChemID | 3547 |
| ScientificBackground | FasudilisaROCK2inhibitorwithsomeactiononPRK2andMSK1(IC50valuesare1.9µM,4µMand5µMrespectively).ItisalsoshowntoinhibitRSK1,RSK2,PKA,AMPKandPKd1.ItisalsoacalciumchannelantagoNISTandvasodilator. |
| References | 1.ShirotaniM.,etal.(1991)J.Pharmacol.Exp.Ther.259(2):738-744. 2.AraiM.,NozawaR.,etal.(1993)Biochem.Pharmacol.46(8):1487-1490. 3.SatohS.,etal.(1996)Br.J.Pharmacol.118(7):1592-1606. 4.SwardK.,etal.(2000)J.Physiol.522:33-49. |
ProductImages
ChemicalstructureofFasudil(SIH-371),aROCKinhibitor.CAS#:103745-39-7.MolecularFormula:C14H17N3O2S•HCl.MolecularWeight:327.83g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
