StressMarq/EX-527/SIH-353-5MG/5-mg
商品编号：
SIH-353-5MG
市场价：
¥1760.00
美元价：
1056.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | EX-527 |
| Description | SIRT1inhibitor |
| Purity | >98%(TLC);NMR(Conforms) |
| CASNo. | 49843-98-3 |
| MolecularFormula | C13H13ClN2O |
| MolecularWeight | 248.7 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solublein18mg/mlDMSOor10mg/mlEthanol |
| Source | Synthetic |
| Appearance | LightYellowSolid |
| SMILES | C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N |
| InChI | InChI=1S/C13H13ClN2O/c14-7-4-5-11-10(6-7)8-2-1-3-9(13(15)17)12(8)16-11/h4-6,9,16H,1-3H2,(H2,15,17) |
| InChIKey | FUZYTVDVLBBXDL-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Harmful-Maybeharmfulifinhaled,swallowed,orabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-AvoidcontactwithskinandeyesHazardStatements:H301–ToxicifswallowedH319–CausesseriouseyeirritationPrecautionaryStatements:P301+P310–Ifswallowed:ImmediatelycallaPOSIONCenterP305+P351+P338:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing. |
| CiteThisProduct | EX-527(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-353) |
BIOLOGicalDescription
| AlternativeNames | 6-Chloro-2,3,4,9-tetrahydro-1Hcarbazole-1-carboxamide(racemic) |
| ResearchAreas | CellSignaling,Epigenetics |
| PubChemID | 5113032 |
| ScientificBackground | SelectiveSIRT1inhibitor(IC50=98nM).DoesnotinhibitotherHDACsorSIRTfamilymembers.Increasesp53acetylationfollowingDNAdamage.Cellpermeable. |
| References | 1.SolomonJ.M.,etal.,(2006)Mol.Cell.Biol.26:28. 2.AndersonJ.L.,etal.,(2011)Mol.Cell43:834. |
ProductImages
ChemicalstructureofEX-527(SIH-353),aSIRT1inhibitor.CAS#:49843-98-3.MolecularFormula:C13H13ClN2O.MolecularWeight:248.7g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
