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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-ERK2 Antibody/SPC-1143D/100-µl
商品详细StressMarq/Anti-ERK2 Antibody/SPC-1143D/100-µl
StressMarq/Anti-ERK2 Antibody/SPC-1143D/100-µl
StressMarq/Anti-ERK2 Antibody/SPC-1143D/100-µl
商品编号: SPC-1143D
市场价: ¥5900.00
美元价: 3540.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameERK2Antibody
Description

RabbitAnti-HumanERK2Polyclonal

SpeciesReactivityHuman,Mouse
ApplicationsWB,AM
AntibodyDilutionWB(1:250);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenSyntheticpeptideofhumanERK2(AA269-283)
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,0.025%Thimerosal
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationPeptideAffinityPurified
ClonalityPolyclonal
SpecificityDetects42kDa.
CiteThisProductStressMarqBiosciencesCat#SPC-1143,RRID:AB_2710973
CertificateofAnalysisA1:250dilutionofSPC-1143wassufficientfordetectionofERK2in10µgofHeLacelllysatebyECLimmunoblotanalysisusinggoatanti-rabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesERKAntibody,ERT1Antibody,ERK2Antibody,ExtracellularSignalRegulatedKinase2Antibody,MAPkinase1Antibody,MAPkinase2Antibody,MAPkinaseisoformp42Antibody,MAPK1Antibody,MAPK2Antibody,Mitogen-activatedproteinkinase1Antibody,Mitogen-activatedproteinkinase2Antibody,MK01_HUMANAntibody,P38Antibody,P40Antibody,P41Antibody,P42MAPKAntibody,PRKM1Antibody,PRKM2Antibodyproteinkinase,proteintyrosinekinaseERK2Antibody
CellularLocalizationCytoplasm,Cytoskeleton,Nucleus,Spindle
AccessionNumberNP_620407
GeneID5594
SwissProtP28482
ScientificBackgroundERK2orMAPK1isaprotein-serine/threoninekinase.Phosphorylatesmanydiffrenttranscriptionfactors,suchasELK1.ActsastranscriptionalrepressorbybindingdirectlytoDNA.EssentialforcyclinD1induction.MAPK1phosphoryltaesBCL2,whichcontributestocellsurvival,thesuppressionoftheapoptoticeffectofBADandup-regulationoftheantiapoptoticproteinMCL-1.Regulatesaccumulationofp53duringDNAdamageresponse.Constitutivelyactiveinmanyhumantumours,supposedlyduetoalteredRAS,RAF,EGFRorotherupstreamelements.ERK/MAPKpathwaywasshowntopromotecellmotiltyandtumourcellmigration.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。