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当前位置： 首页 > 产品中心 > DNA_buffer_solution > StressMarq/Anti-ErbB2 Antibody (pTyr735)/SPC-968D-A594/100-µl
商品详细StressMarq/Anti-ErbB2 Antibody (pTyr735)/SPC-968D-A594/100-µl
StressMarq/Anti-ErbB2 Antibody (pTyr735)/SPC-968D-A594/100-µl
StressMarq/Anti-ErbB2 Antibody (pTyr735)/SPC-968D-A594/100-µl
商品编号： SPC-968D-A594
市场价： ¥6840.00
美元价： 4104.00
产地： 美国(厂家直采)
公司：
产品分类： 上样缓冲液
公司分类： DNA_buffer_solution
联系Q Q： 3392242852
电话号码： 4000-520-616
电子邮箱： info@ebiomall.com
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商品介绍

Overview:

Product Name ErbB2 Antibody (pTyr735)
Description

Rabbit Anti-Human ErbB2 (pTyr735) Polyclonal

Species Reactivity Human
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A phospho-specific peptide corresponding to residues surrounding Tyr735 of human ErbB2 (AA732-739)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 137.91 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-968, RRID: AB_2707823
Certificate of Analysis A 1:250 dilution of SPC-968 was sufficient for detection of ErbB2 (pTyr735) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names ER Alpha antibody, ER Beta antibody, Era antibody, Erb antibody, Erb2 antibody, ESR antibody, ESR1 antibody, ESR1_HUMAN antibody, ESR2 antibody, ESRA antibody, ESRB antibody, Estr antibody, Estra antibody, Estradiol Receptor alpha antibody, ESTRB antibody, Estrogen receptor 1 (alpha) antibody, Estrogen Receptor 1 antibody, Estrogen receptor 2 (ER beta) antibody, NR3A1 antibody, NR3A2 antibody, Nuclear receptor subfamily 3 group A member 1 antibody, Nuclear receptor subfamily 3 group A member 2 antibody, RNESTROR antibody
Research Areas Cancer, Cell Signaling, Oncoproteins, Protein Phosphorylation, Receptor Tyrosine Kinases, Serine / Threonine Kinases, Tumor Biomarkers, Tyrosine Kinases
Cellular Localization Cytoplasm, Cell membrane, Nucleus
Accession Number NP_004439
Gene ID 2064
Swiss Prot P04626
Scientific Background ErbB2 is a receptor-tyrosine kinase of the epidermal growth factor receptor family,that is activated upon binding NRG with ErbB3. NRG acts as an autocrine factor produced in ovarian carcinomas. ERBB2 needs a coreceptor for ligand binding. Activates MAPK and PI3K pathways and is involved in cell proliferation, prolonging and enhancing survival signals, differentiation and apoptosis. Amplification and overexpression of ERBB2 is associated with numerous cancers. The increase of ERBB2 protein in breast tumour can be up to 100-fold.

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 ATTO 594
Overview:

  • High fluorescence yield
  • High photostability
  • Very hydrophilic
  • Excellent solubility in water
  • Very little aggregation
  • New dye with net charge of -1
  • Molar Mass: 1137 g/mol

ATTO 594 Datasheet

 ATTO 594 Fluorophore Excitation and Emission SpectrumOptical Properties:

λex = 601 nm

λem = 627 nm

εmax = 1.2×105

Φf = 0.85

τfl = 3.5 ns

Brightness = 102

Laser = 594 nm

Filter set = Texas Red®

 

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StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
公司介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒
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