STRESTMARQ/抗ENaCβ抗体[7B8]/SMC-240D-A565/100-微克-免疫在线蚂蚁淘旗下平台

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商品详细STRESTMARQ/抗ENaCβ抗体[7B8]/SMC-240D-A565/100-微克

STRESTMARQ/抗ENaCβ抗体[7B8]/SMC-240D-A565/100-微克

商品编号： SMC-240D-A565

品牌： StressMarq Biosciences

市场价： ¥6840.00

美元价： 4104.00

产地：美国(厂家直采)

公司：

产品分类：上样缓冲液

公司分类： DNA_buffer_solution

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Overview:

ProductName ENaCbetaAntibody

Description

MouseAnti-RatENaCbetaMonoclonalIgG1

SpeciesReactivity Mouse

Applications WB,IHC

AntibodyDilution WB(1:1000);IHC(1:150);optimaldilutionsforassaysshouldbedeterminedbytheuser.

HostSpecies Mouse

ImmunogenSpecies Rat

Immunogen SyntheticpeptidefromtheC-terminalofRatENaCbeta(aa.617-638)

Concentration 1mg/ml

Conjugates

AlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBuffer	PBSpH7.4,50%glycerol,0.09%sodiumazide
StorageTemperature	-20ºC
ShippingTemperature	BlueIceor4ºC
Purification	ProteinGPurified
Clonality	Monoclonal
CloneNumber	7B8
Isotype	IgG1
Specificity	Detects~87kDa.
CiteThisProduct	StressMarqBiosciencesCat#SMC-240,RRID:AB_2699538
CertificateofAnalysis	A1:1000dilutionofSMC-240wassufficientfordetectionofENaCbetain15µgofMousewholekidneylysatebyECLimmunoblotanalysisusinggoatanti-mouseIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNames	SCNN1BAntibody,AmiloridesensitivesodiumchannelsubunitbetaAntibody,Amiloride-sensitivesodiumchannelbeta-subunitAntibody,BetaENaCAntibody,BetaNaCHAntibody,ENaCbetaAntibody,ENaCBAntibody,EpithelialNa(+)channelsubunitbetaAntibody,EpithelialNa+channelbetasubunitAntibody,EpithelialNa+channelsubunitbetaAntibody,Epithelialsodiumchannelbeta2subunitAntibody,Epithelialsodiumchannelbeta3subunitAntibody,Nonvoltagegatedsodiumchannel1betasubunitAntibody,Nonvoltagegatedsodiumchannel1subunitbetaAntibody,Nonvoltage-gatedsodiumchannel1betasubunitAntibody,SCNEBAntibody,SCNN1BAntibody,Sodiumchannelnonvoltagegated1beta(Liddlesyndrome)Antibody,Sodiumchannelnonvoltagegated1betaAntibody
ResearchAreas	EpithelialSodiumChannels(ENaC),IonChannels,Neuroscience,SodiumChannels
CellularLocalization	Apicalcellmembrane
AccessionNumber	NP_036780
GeneID	24767
SwissProt	P37090
ScientificBackground	TheEpithelialSodiumChannel(ENaC)isamembraneionchannelpermeabletoNa+ions.Itislocatedintheapicalplasmamembraneofepitheliainthekidneys,lung,colon,andothertissueswhereitplaysaroleintransepithelialNa+-iontransport(1).SpecificallyNa+transportviaENaCoccursacrossmanyepithelialsurfaces,andplaysakeyroleinregulatingsaltandwaterabsorption(2).ENaCsarecomposedofthreestructurallyrelatedsubunitsthatformatetramericchannel,alpha,beta,andgamma.Theexpressionofitsalphaandbetasubunitsisenhancedaskeratinocytesdifferentiate(3,4).Thebetaandgamma-ENaCsubunitsareessentialforedemafluidtoexertitsmaximaleffectonnetfluidabsorptionbydistallungepithelia(5).Andithasbeenconcludedthatthesubunitsaredifferentiallyexpressedintheretinaofmicewithocularhypertension,thereforetheup-regulationofalpha-ENaCproteinscouldserveasaprotectionmechanismagainstelevatedintraocularpressure(6).
References	1.KakizoeY.,etal.(2009)JHpyertens.27(8):1679-1689. 2.GuY.(2008)JCellPhysiol.216(2):453-457. 3.BrunsJ.B.(2003)AmJPhysiolRenalPhysiol.285(4):F600-F609. 4.MauroT.,etal.(2002)JInvestDermatol.118(4):589-594. 5.EliasN.,etal.(2007)AmJPhysiolLungCellMolPhysiol.293(3):L537-45. 6.DykaF.M.,MayC.A.andEnzR.(2005)JNeuRochem.94(1):120-128.

ProductImages

<p>Immunohistochemistry analysis using Mouse Anti-ENaC beta Monoclonal Antibody, Clone 7B8 (SMC-240). Tissue: Kidney (cortex). Species: Mouse. Primary Antibody: Mouse Anti-ENaC beta Monoclonal Antibody (SMC-240) at 1:150. Localization: Collecting duct principal cells. Magnification: 60X.</p>

ImmunohistochemistryanalysisusingMouseAnti-ENaCbetaMonoclonalAntibody,Clone7B8(SMC-240).Tissue:Kidney(cortex).Species:Mouse.PrimaryAntibody:MouseAnti-ENaCbetaMonoclonalAntibody(SMC-240)at1:150.Localization:Collectingductprincipalcells.Magnification:60X.

<p>Western Blot analysis of Mouse Whole kidney homogenates showing detection of ~87kDa ENaC beta protein using Mouse Anti-ENaC beta Monoclonal Antibody, Clone 7B8 (SMC-240). Lane 1: Molecular Weight Ladder (MW). Lane 2: Low-salt diet. Lane 3: Normal-salt diet. Load: 20 µg. Primary Antibody: Mouse Anti-ENaC beta Monoclonal Antibody (SMC-240) at 1:1000. Predicted/Observed Size: ~87kDa.</p>

WesternBlotanalysisofMouseWholekidneyhomogenatesshowingdetectionof~87kDaENaCbetaproteinusingMouseAnti-ENaCbetaMonoclonalAntibody,Clone7B8(SMC-240).Lane1:MolecularWeightLadder(MW).Lane2:Low-saltdiet.Lane3:Normal-saltdiet.Load:20µg.PrimaryAntibody:MouseAnti-ENaCbetaMonoclonalAntibody(SMC-240)at1:1000.Predicted/ObservedSize:~87kDa.

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ATTO565

Overview:

Highfluorescenceyield
HighthermalandphotostABIlity
Goodsolubilityinpolarsolvents
Excellentsolubilityinwater
Verylittleaggregation
Rhodaminedyederivative
MolarMass:611g/mol

ATTO565Datasheet

ATTO 565 Fluorophore Excitation and Emission Spectra

OpticalProperties:

λ_ex =563nm

λ_em=592nm

ε_max=1.2×10⁵

Φ_f= 0.9

τ_fl =3.4n

Brightness=10

Laser =532nm

Filterset = TRITC

品牌介绍

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。

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