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当前位置: 首页 > 产品中心 > DNA_buffer_solution > 应力MARQ/抗EGFR抗体(pTyr869)/SPC-961D-A390/100-µl
商品详细应力MARQ/抗EGFR抗体(pTyr869)/SPC-961D-A390/100-µl
应力MARQ/抗EGFR抗体(pTyr869)/SPC-961D-A390/100-µl
应力MARQ/抗EGFR抗体(pTyr869)/SPC-961D-A390/100-µl
商品编号: SPC-961D-A390
市场价: ¥6860.00
美元价: 4116.00
产地: 美国(厂家直采)
公司:
产品分类: 上样缓冲液
公司分类: DNA_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name EGFR Antibody (pTyr869)
Description

Rabbit Anti-Human EGFR (pTyr869) Polyclonal

Species Reactivity Human
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A phospho-specific peptide corresponding to residues surrounding Tyr869 of human EGFR (AA866-873)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 134.277 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-961, RRID: AB_2707697
Certificate of Analysis A 1:250 dilution of SPC-961 was sufficient for detection of EGFR (pTyr869) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names Avian erythroblastic leukemia viral (v erb b) oncogene homolog Antibody, Cell growth inhibiting protein 40 Antibody, Cell proliferation inducing protein 61 Antibody, Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) Antibodyy, Epidermal growth factor receptor Antibody, ERBB Antibody, ERBB1 Antibody, Errp Antibody, HER1Antibody, mENA Antibody, NISBD2 Antibodyy, PIG61 Antibody, SA7 Antibody, wa2 Antibody, Wa5 Antibody
Research Areas Cancer, Cell Signaling, Oncoproteins, Protein Phosphorylation, Receptor Tyrosine Kinases, Receptors, Tumor Biomarkers, Tyrosine Kinases
Cellular Localization Cell membrane, Endoplasmic Reticulum, Endosome, Golgi apparatus, Nucleus
Accession Number NP_005219
Gene ID 1956
Swiss Prot P00533
Scientific Background EGFR is a receptor-tyrosine kinase that is activated upon binding epidermal growth factor (EGF) and transforming growth factor-alpha (TGFalpha). Binding of EGF ellicits a pro-growth and anti-apoptotic response through the Ras pathway. Missense mutations and deletions are common in a variety of cancers.

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  ATTO 390
Overview:

  • High fluorescence yield
  • Large Stokes-shift (89 nm)
  • Good photostability
  • Moderately hydrophilic
  • Good solubility in polar solvents
  • Coumarin derivate, uncharged
  • Low molar mass: 343.42 g/mol 

ATTO 390 Datasheet

ATTO 390 Fluorescent Dye Excitation and Emission SpectraOptical Properties:

λex = 390 nm

λem = 479 nm

εmax = 2.4×104

Φf = 0.90

τfl = 5.0 ns

Brightness = 21.6

Laser = 365 or 405 nm

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。