STRESS MARQ/E-4031/SIH-317-10MG/10MG
商品编号：
SIH-317-10MG
市场价：
¥2800.00
美元价：
1680.00
产品分类：
上样缓冲液
公司分类：
DNA_buffer_solution
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | E-4031 |
| Description | Hergchannelblocker |
| Purity | >98%(TLC:CH2Cl2/CH3OH;9:1with1%NH4OH;Silicagel60;Rf=0.39);NMRconforms |
| CASNo. | 113558-89-7 |
| MolecularFormula | C₂₁H₂₇N₃O₃S·2HCl·2H₂O |
| MolecularWeight | 510.5 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleinwater(100mg/ml)andwarmDMSO(25mg/ml) |
| Source | Synthetic |
| Appearance | Whitesolid |
| SMILES | CC1=NC(=CC=C1)CCN2CCC(CC2)C(=O)C3=CC=C(C=C3)NS(=O)(=O)C.O.O.Cl.Cl |
| InChI | InChI=1S/C21H27N3O3S.2ClH.2H2O/c1-16-4-3-5-19(22-16)12-15-24-13-10-18(11-14-24)21(25)17-6-8-20(9-7-17)23-28(2,26)27;;;;/h4-9,18,23H,10-15H2,1-2H3;2*1H;2*1H2 |
| InChIKey | AJNFQUKPBCGJKX-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionHazardPhrases:H302-H315-H317-H318-H335PrecautionaryPhrases:P261-P280-P305+P351+P338 |
| CiteThisProduct | E-4031(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-317) |
BIOLOGicalDescription
| AlternativeNames | N-[4-[[1-[2-(6-Methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]methanesulfonamidedihydrochloride,dihydrate |
| ResearchAreas | IonChannels,Neuroscience |
| PubChemID | 5312116 |
| ScientificBackground | E-4031actsonaspecificclassofvoltagegatedpotassiumchannels,thehERGchannels.Itdoesthisbybindingtotheopenchannels,althoughitsstructuraltargetisunclear(1-4).Itisalsoananti-arrhythmicdrug(5). |
| References | 1.GerlachA.C.,StoehrS.J.,CastleN.A.(2010)MolPharmacol.77(1):56-68. 2.PerrinM.J.,etal.(2008)ProgBiophysMolBiol.98:137-148. 3.SanguinettiM.C.,JurkiewiczN.K.(1990)JGenPhysiol.96:195-215. 4.SpectorP.S.,CurranM.E.,KeatingM.T.,andSanguinettiM.C.(1996)CircRes.78:499-503. 5.MiyakeK.,etal.(1990)JMedChem.33:903. |
ProductImages
ChemicalstructureofE-4031(SIH-317),aHergchannelblocker.CAS#:113558-89-7.MolecularFormula:C₂₁H₂₇N₃O₃S·2HCl·2H₂O.MolecularWeight:510.5g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
