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当前位置: 首页 > 产品中心 > DNA_buffer_solution > STRESS MARQ/抗DUSP11抗体/SPC-1119D-P594/100-µl
商品详细STRESS MARQ/抗DUSP11抗体/SPC-1119D-P594/100-µl
STRESS MARQ/抗DUSP11抗体/SPC-1119D-P594/100-µl
STRESS MARQ/抗DUSP11抗体/SPC-1119D-P594/100-µl
商品编号: SPC-1119D-P594
市场价: ¥6980.00
美元价: 4188.00
产地: 美国(厂家直采)
公司:
产品分类: 上样缓冲液
公司分类: DNA_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameDUSP11Antibody
Description

RabbitAnti-HumanDUSP11Polyclonal

SpeciesReactivityHuman,Mouse
ApplicationsWB,AM
AntibodyDilutionWB(1:250);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenAsyntheticpeptideofhumanDUSP11(AA290-304)
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,0.025%Thimerosal
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationPeptideAffinityPurified
ClonalityPolyclonal
SpecificityDetects~38kDa.
CiteThisProductStressMarqBiosciencesCat#SPC-1119,RRID:AB_2710541
CertificateofAnalysisA1:250dilutionofSPC-1119wassufficientfordetectionofDUSP11in10µgofhumankidneylysatebyECLimmunoblotanalysisusinggoatanti-rabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesDualspecificityphosphatase11antibody,Dualspecificityproteinphosphatase11antibody,DUS11_HUMANantibody,DUSP11antibody,PhosphatasethatinteractswithRNA/RNPcomplex1antibody,PIR1antibody,RNA/RNPcomplex1interactingantibody,RNA/RNPcomplexinteractingphosphataseantibody
CellularLocalizationNucleus
AccessionNumberNP_003575
GeneID8446
SwissProtO75319
ScientificBackgroundDUSP11isamemberofthedualspecificityproteinphosphatasesubfamily.Thesephosphatasesinactivatetheirtargetkinasesbydephosphorylatingboththephosphoserine/threonineandphosphotyrosineresidues.Theynegativelyregulatemembersofthemitogen-activatedprotein(MAP)kinasesuperfamily(MAPK/ERK,SAPK/JNK,p38),whichisassociatedwithcellularproliferationanddifferentiation.DifferentmembersofthefamilyofdualspecificityphosphatasesshowdistinctsubstratespecificitiesforvariousMAPkinases,differenttissuedistributionandsubcellularlocalization,anddifferentmodesofinducibilityoftheirexpressionbyextracellularstimuli.ThisgeneproductislocalizedtothenucleusandbindsdirectlytoRNAandsplicingfactors,andthusitissuggestedtoparticipateinnuclearmRNAmetabolism.

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 PE/ATTO594
PE/ATTO594isatandemconjugate,wherePEisexcitedat535nmandtransfersenergytoATTO594viaFRET(fluorescenceresonanceenergytransfer),whichemitsat627nm.
Overview:
  • Highfluorescenceyield
  • HighphotostABIlity
  • Veryhydrophilic
  • Excellentsolubilityinwater
  • Verylittleaggregation

PE/ATTO594Datasheet

PE-ATTO 594 Fluorophore Conjugate Excitation and Emission SpectraOpticalProperties:

λex =535nm

λem =627 nm

Laser = 488to561nm

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。