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当前位置: 首页 > 产品中心 > DNA_buffer_solution > STRESS MARQ/抗DUSP11抗体/SPC-1119D-HRP/100-µl
商品详细STRESS MARQ/抗DUSP11抗体/SPC-1119D-HRP/100-µl
STRESS MARQ/抗DUSP11抗体/SPC-1119D-HRP/100-µl
STRESS MARQ/抗DUSP11抗体/SPC-1119D-HRP/100-µl
商品编号: SPC-1119D-HRP
市场价: ¥6600.00
美元价: 3960.00
产地: 美国(厂家直采)
公司:
产品分类: 上样缓冲液
公司分类: DNA_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameDUSP11Antibody
Description

RabbitAnti-HumanDUSP11Polyclonal

SpeciesReactivityHuman,Mouse
ApplicationsWB,AM
AntibodyDilutionWB(1:250);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenAsyntheticpeptideofhumanDUSP11(AA290-304)
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,0.025%Thimerosal
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationPeptideAffinityPurified
ClonalityPolyclonal
SpecificityDetects~38kDa.
CiteThisProductStressMarqBiosciencesCat#SPC-1119,RRID:AB_2710541
CertificateofAnalysisA1:250dilutionofSPC-1119wassufficientfordetectionofDUSP11in10µgofhumankidneylysatebyECLimmunoblotanalysisusinggoatanti-rabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesDualspecificityphosphatase11antibody,Dualspecificityproteinphosphatase11antibody,DUS11_HUMANantibody,DUSP11antibody,PhosphatasethatinteractswithRNA/RNPcomplex1antibody,PIR1antibody,RNA/RNPcomplex1interactingantibody,RNA/RNPcomplexinteractingphosphataseantibody
CellularLocalizationNucleus
AccessionNumberNP_003575
GeneID8446
SwissProtO75319
ScientificBackgroundDUSP11isamemberofthedualspecificityproteinphosphatasesubfamily.Thesephosphatasesinactivatetheirtargetkinasesbydephosphorylatingboththephosphoserine/threonineandphosphotyrosineresidues.Theynegativelyregulatemembersofthemitogen-activatedprotein(MAP)kinasesuperfamily(MAPK/ERK,SAPK/JNK,p38),whichisassociatedwithcellularproliferationanddifferentiation.DifferentmembersofthefamilyofdualspecificityphosphatasesshowdistinctsubstratespecificitiesforvariousMAPkinases,differenttissuedistributionandsubcellularlocalization,anddifferentmodesofinducibilityoftheirexpressionbyextracellularstimuli.ThisgeneproductislocalizedtothenucleusandbindsdirectlytoRNAandsplicingfactors,andthusitissuggestedtoparticipateinnuclearmRNAmetabolism.

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HRP(HorserADIshperoxidase)

Properties:

  • Enzymaticactivityisusedtoamplifyweaksignalsandincreasevisibilityofatarget
  • Readilycombineswithhydrogenperoxide(H2O2)toformHRP-H2O2complexwhichcanoxidizevarioushydrogendonors
  • Catalyzestheconversionof:
    • Chromogenicsubstrates(e.g.TMB,DAB,ABTS)intocolouredproducts
    • Chemiluminescentsubstrates(e.g.luminolandisoluminol)intolightemittingproductsviaenhancedchemiluminescence(ECL)
    • Fluorogenicsubstrates(e.g.tyramine,homovanillicacid,and4-hydroxyphenylaceticacid)intofluorescentproducts
  • Highturnoverrateenablesrapidgenerationofastrongsignal
  • 44kDaglycoprotein
  • Extinctioncoefficient:100(403nm)
  • Applications:Westernblot,immunohistochemistry,andELISA

HRPDatasheet

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。