STRESTMARQ/盐酸阿霉素/SIH-390-50MG/50MG
商品编号：
SIH-390-50MG
市场价：
¥8300.00
美元价：
4980.00
产品分类：
上样缓冲液
公司分类：
DNA_buffer_solution
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | DoxorubicinHydrochloride |
| Description | Autophagyinducer |
| Purity | >98%(TLC);NMR(Conforms) |
| CASNo. | 25316-40-9 |
| MolecularFormula | C27H29NO11•HCl |
| MolecularWeight | 580 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inducer |
| Solubility | Solubleinwater(50mM). |
| Source | Synthetic |
| Appearance | Redsolid |
| SMILES | [[email protected]]2(OC1OC(C(O)C(N)C1)C)C[[email protected]@](O)(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)C(=O)CO.[H+].[Cl-] |
| InChI | InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h4-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3 |
| InChIKey | MWWSFMDVAYGXBV-RUELKSSGSA-N |
| SafetyPhrases | Classification:NotWHMIScontrolled.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H302-Harmfulifswallowed.H350-Maycausecancer.Precautionarystatements:P201-Obtainspecialinstructionsbeforeuse.P308+P313-IFexposedorconcerned:Getmedicaladvice/attention. |
| CiteThisProduct | DoxorubicinHydrochloride(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-390) |
BIOLOGicalDescription
| AlternativeNames | Adriamycin |
| ResearchAreas | Cancer,Autophagy |
| PubChemID | 443939 |
| ScientificBackground | DoxorubicinHydrochlorideisusedinaclinicalsettingforthetreatmentofawiderangeofcancers,includinglymphomas,leukemias,andsolidtumorsofthebreast,pancreas,stomach,bladder,andovaries.ThisdrugintercalatesintoDNAandthereforeinducesapoptosisbyhinderingcellularfunctionslikereplicationandtranscriptionbyspecificallyinhibitingthebindingofreversetranscriptase,RNApolymeraseandtopoisomeraseII.Doxorubicinhassomeadverseeffectsforpatientsincludingimmunosuppressiveeffectscausedbyhematologictoxicity.Doxorubicinhasalsobeenshowntoinduceautophagyinaspecies-specificmanner. |
| References | 1.Kusayanagi,T.etal.(2012).BioorgMedChem.20(21):6248-55. 2.Chen,N.T.etal.(2012).PLoSOne.7(9). 3.Patel,S.etal.(1997).MolPharmacol.52(4):658-66. 4.Cutts,S.etal.(1996).JBiolChem.271(10):5422-9. 5.Danesi,R.etal.(2004).TransplantProc.36(3):703-4. 6.Dirks-Naylor,A.(2013).LifeSci.93(24):913-6. |
ProductImages
ChemicalstructureofDoxorubicinHydrochloride(SIH-390),aAutophagyinducer.CAS#:25316-40-9.MolecularFormula:C27H29NO11.HCl.MolecularWeight:580g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
