4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > DNA_buffer_solution > StressMarq/抗双重皮质素抗体/SPC-1294D-BI/100-µl
商品详细StressMarq/抗双重皮质素抗体/SPC-1294D-BI/100-µl
StressMarq/抗双重皮质素抗体/SPC-1294D-BI/100-µl
StressMarq/抗双重皮质素抗体/SPC-1294D-BI/100-µl
商品编号: SPC-1294D-BI
市场价: ¥5960.00
美元价: 3576.00
产地: 美国(厂家直采)
公司:
产品分类: 上样缓冲液
公司分类: DNA_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name Doublecortin Antibody
Description

Rabbit Anti-Human Doublecortin Polyclonal

Species Reactivity Human, Mouse, Rat
Applications WB, ELISA
Antibody Dilution WB (1:1000), ELISA (1:10000); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen Synthesized unphosphorylated peptide derived from human Doublecortin around the phosphorylation site of serine 376 (P-T-SP-P-G).
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Affinity Purified
Clonality Polyclonal
Isotype IgG
Specificity Detects ~45kDa, endogenous levels of total Doublecortin protein.
Cite This Product StressMarq Biosciences Cat# SPC-1294, RRID: AB_2713097
Certificate of Analysis A 1:1000 dilution of SPC-1294 was sufficient for detection of Doublecortin in 10 µg of Jurkat cell lysates by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names DBCN Antibody, Dbct Antibody, DC Antibody, DCX Antibody, DCX_HUMAN Antibody, Doublecortex Antibody, Doublin Antibody, FLJ51296 Antibody, Lis X Antibody, Lis-X Antibody, Lissencephalin X Antibody, Lissencephalin-X Antibody, Lissencephaly X linked Antibody, Lissencephaly X linked doublecortin Antibody, LISX Antibody, Neuronal migration protein doublecortin Antibody, OTTHUMP00000023859 Antibody, OTTHUMP00000023860 Antibody, OTTHUMP00000216315 Antibody, OTTHUMP00000216316 Antibody, SCLH Antibody, XLIS Antibody
Research Areas Cell Markers, Cell Structure, Neuroscience
Cellular Localization Cytoplasm, Cell projection, Cytoskeleton, Cytosol
Accession Number NP_000546.2
Gene ID 1641
Swiss Prot O43602
Scientific Background Neuronal migration protein doublecortin is a protein that in humans is encoded by the DCX gene, also known as doublin or lissencephalin-X. Doublecortin (DCX) is a microtubule-associated protein expressed almost exclusively in immature neurons. Neuronal precursors begin to express DCX shortly after exiting the cell cycle, and continue to express DCX for 2-3 weeks as the cells mature into neurons. It seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway.
References 1. Oomen C.A. et al. (2009) PLoS ONE 4 (1): e3675.
2. Brown J.P. et al. (2003) J. Comp. Neurol. 467 (1): 1–10.
3. Couillard-Despres S. et al. (2005) Eur. J. Neurosci. 21 (1): 1–14.

Product Images

<p>Western blot analysis of Human Jurkat cell lysates showing detection of ~40-45kDa Doublecortin protein using Rabbit Anti-Doublecortin Polyclonal Antibody (SPC-1294). Lane 1: Human Jurkat. Lane 2: Human Jurkat treated with the immunizing peptide. Primary Antibody: Rabbit Anti-Doublecortin Polyclonal Antibody (SPC-1294) at 1:1000. Predicted/Observed Size: ~40-45kDa.</p>

Western blot analysis of Human Jurkat cell lysates showing detection of ~40-45kDa Doublecortin protein using Rabbit Anti-Doublecortin Polyclonal Antibody (SPC-1294). Lane 1: Human Jurkat. Lane 2: Human Jurkat treated with the immunizing peptide. Primary Antibody: Rabbit Anti-Doublecortin Polyclonal Antibody (SPC-1294) at 1:1000. Predicted/Observed Size: ~40-45kDa.

Product Citations (0)

Currently there are no citations for this product.

BiotinBiotin Conjugate Structure

Properties:

  • Binds tetrameric avidin proteins including Streptavidin and neuravidin with very high affinity
  • Molar mass: 244.31 g/mol
  • Formula: C10H16N2O3S
  • Applications: Western blot, immunohistochemistry, and ELISA

Biotin Datasheet

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。