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当前位置: 首页 > 产品中心 > DNA_buffer_solution > STRESTMARQ/多索啡/SIH-443-5MG/5-mg
商品详细STRESTMARQ/多索啡/SIH-443-5MG/5-mg
STRESTMARQ/多索啡/SIH-443-5MG/5-mg
STRESTMARQ/多索啡/SIH-443-5MG/5-mg
商品编号: SIH-443-5MG
市场价: ¥1600.00
美元价: 960.00
产地: 美国(厂家直采)
公司:
产品分类: 上样缓冲液
公司分类: DNA_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameDorsomorphin
Description

AMPKkinaseinhibitor

Purity>98%(HPLC)
CASNo.866405-64-3
MolecularFormulaC24H25N5O
MolecularWeight399.5

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleinDMSO(4mg/ml,warm)
SourceSynthetic
AppearanceYellowsolid
SMILESC1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3
InChIInChI=1S/C24H25N5O/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20/h4-11,16-18H,1-3,12-15H2
InChIKeyXHBVYDAKJHETMP-UHFFFAOYSA-N
SafetyPhrasesClassification:Acutetoxicity,Oral(Category4),H302Acutetoxicity,Inhalation(Category4),H332Acutetoxicity,Dermal(Category4),H312SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H302+H312+H332Harmfulifswallowed,incontactwithskinorifinhaledPrecautionarystatements:P261Avoidbreathingdust/fume/gas/mist/vapours/spray.P264Washskinthoroughlyafterhandling.P270Donoteat,drinkorsmokewhenusingthisproduct.P271Useonlyoutdoorsorinawell-ventilatedarea.P280Wearprotectivegloves/protectiveclothing.P301+P312IFSWALLOWED:CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P302+P352IFONSKIN:Washwithplentyofsoapandwater.P304+P340IFINHALED:Removevictimtofreshairandkeepatrestinapositioncomfortableforbreathing.
CiteThisProductDorsomorphin(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-443)

BIOLOGicalDescription

AlternativeNamesAMPKInhibitor,CompoundC,6-[4-(2-Piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
ResearchAreasCancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors
PubChemID11524144
ScientificBackgroundDorsomorphinisapotentandselectiveandreversIBLeinhibitorofAMP-kinase,doingsoinanATP-competitivemanner.ItisalsoaselectiveinhibitorofBonemorphogeneticprotein(BMP)signaling.
References1.VucicevicL.,etal.(2011)Autophagy7(1):40–50.
2.YuP.B.,etal.(2008).Nat.Chem.Biol.4(1):33–41.

ProductImages

<p>Chemical structure of Dorsomorphin (SIH-443), a AMPK kinase inhibitor. CAS #: 866405-64-3. Molecular Formula: C24H25N5O. Molecular Weight: 399.5 g/mol.</p>

ChemicalstructureofDorsomorphin(SIH-443),aAMPKkinaseinhibitor.CAS#:866405-64-3.MolecularFormula:C24H25N5O.MolecularWeight:399.5g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。