StressMarq/Doramapimod/SIH-442-5MG/5-mg
商品编号:
SIH-442-5MG
市场价:
¥1700.00
美元价:
1020.00
产品分类:
上样缓冲液
公司分类:
DNA_buffer_solution
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Overview:
ProductName | Doramapimod |
Description | p38MAPkinaseinhibitor |
Purity | >99%(HPLC) |
CASNo. | 285983-48-4 |
MolecularFormula | C31H37N5O3 |
MolecularWeight | 527.7 |
Properties
StorageTemperature | -20ºC |
ShippingTemperature | ShippedAmbient |
ProductType | Inhibitor |
Solubility | SolubleinDMSO |
Source | Synthetic |
Appearance | Whitesolid |
SMILES | C2=CC(=C1C=CC=CC1=C2NC(NC3=CC(=N[N]3C4=CC=C(C=C4)C)C(C)(C)C)=O)OCCN5CCOCC5 |
InChI | InChI=1S/C31H37N5O3/c1-22-9-11-23(12-10-22)36-29(21-28(34-36)31(2,3)4)33-30(37)32-26-13-14-27(25-8-6-5-7-24(25)26)39-20-17-35-15-18-38-19-16-35/h5-14,21H,15-20H2,1-4H3,(H2,32,33,37) |
InChIKey | MVCOAUNKQVWQHZ-UHFFFAOYSA-N |
SafetyPhrases | Classification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection. |
CiteThisProduct | Doramapimod(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-442) |
BIOLOGicalDescription
AlternativeNames | JNKInhibitorXVII,BIRB796,1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea |
ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
PubChemID | 156422 |
ScientificBackground | Doramapimodisahighlypotentandselectiveinhibitorofp38αMAPK.ItspecificallyblocksTNFαrelease. |
References | 1.PargellisC.,etal.(2002).NatStructuralBiol.9(4):268–272. |
ProductImages
ChemicalstructureofDoramapimod(SIH-442),ap38MAPkinaseinhibitor.CAS#:285983-48-4.MolecularFormula:C31H37N5O3.MolecularWeight:527.7g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。