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当前位置: 首页 > 产品中心 > DNA_buffer_solution > STRESTMARQ/抗DOK3抗体(pTyr398)/SPC-958D-FITC/100-µl
商品详细STRESTMARQ/抗DOK3抗体(pTyr398)/SPC-958D-FITC/100-µl
STRESTMARQ/抗DOK3抗体(pTyr398)/SPC-958D-FITC/100-µl
STRESTMARQ/抗DOK3抗体(pTyr398)/SPC-958D-FITC/100-µl
商品编号: SPC-958D-FITC
市场价: ¥6680.00
美元价: 4008.00
产地: 美国(厂家直采)
公司:
产品分类: 上样缓冲液
公司分类: DNA_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameDOK3Antibody(pTyr398)
Description

RabbitAnti-HumanDOK3(pTyr398)Polyclonal

SpeciesReactivityHuman
ApplicationsWB,AM
AntibodyDilutionWB(1:250);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenAphospho-specificpeptidecorrespondingtoresiduessurroundingTyr397ofhumanEML4(AA395-401)
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,0.025%Thimerosal
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationPeptideAffinityPurified
ClonalityPolyclonal
SpecificityDetects53.288kDa.
CiteThisProductStressMarqBiosciencesCat#SPC-958,RRID:AB_2707643
CertificateofAnalysisA1:250dilutionofSPC-958wassufficientfordetectionofDOK3(pTyr398)in10µgofHepG2celllysatebyECLimmunoblotanalysisusinggoatanti-rabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesDockingprotein3Antibody,DOKLikeProteinAntibody,Dok3Antibody,DOKLPendingAntibody,Downstreamoftyrosinekinase3Antibody,p62DOKLikeProteinAntibody
ResearchAreasCancer,CellSignaling,MAPKPathway,ProteinPhosphorylation,Serine/ThreonineKinases
CellularLocalizationCytoplasm,Cellmembrane
AccessionNumberNP_001138347
GeneID79930
SwissProtQ7L591
ScientificBackgroundDOK3isamemberofaclassof“docking”proteinswhichcontainmultipletyrosineresiduesandputativeSH2bindingsites.DOK3isanadapterinvolvedintherecruitmentofinhibitorymoleculesandishighlyexpressedinBcellsandmacrophages.Immunoreceptor-mediatedcellularactivationinducestyrosinephosphorylationofDOK3.Uponphosphorylation,DOK3bindsto5’inositolphosphataseSHIPandtheproteintyrosinekinaseCsk.DOK3mayplayasignificantroleinthenegativeregulationofimmunoreceptorsignalinginhemopoieticcells.

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 FITC(Fluorescein)
Overview:
  • Excellentfluorescencequantumyield
  • Highrateofphotobleaching
  • Goodsolubilityinwater
  • Broademissionspectrum
  • pHdependentspectra
  • Molecularformula:C20H12O5
  • Molarmass:332.3g/mol

FITC-Fluorescent-conjugate

FITC Fluorescein Fluorophore Excitation and Emission SpectraOpticalProperties:

λex =494 nm

λem=520 nm

εmax=7.3×104

Φf= 0.92

τfl =5.0ns

Brightness= 67.2

Laser = 488 nm

Filterset = FITC

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。