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StressMarq/Dimethyloxaloylglycine (DMOG)/SIH-382-10MG/10-mg
StressMarq/Dimethyloxaloylglycine (DMOG)/SIH-382-10MG/10-mg
商品编号：
SIH-382-10MG
市场价：
¥1140.00
美元价：
684.00
产品分类：
电泳缓冲液
公司分类：
Electrophoretic_buffer
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Dimethyloxaloylglycine(DMOG) |
| Description | Prolyl-4-hydroxylaseinhibitor |
| Purity | >99% |
| CASNo. | 89464-63-1 |
| MolecularFormula | C6H9NO5 |
| MolecularWeight | 175.1 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(>25mg/ml),100%ethanol(>25mg/ml)ordimethylformamide,orPBSpH7.2(10mg/ml) |
| Source | Synthetic |
| Appearance | Off-whitesolid |
| SMILES | C(C(=O)OC)NC(C(=O)OC)=O |
| InChI | InChI=1S/C6H9NO5/c1-11-4(8)3-7-5(9)6(10)12-2/h4H2,1-2H3,(H,7,9) |
| InChIKey | BNJOZDZCRHCODO-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Caution.Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-AvoidcontactwithskinandeyesHazardStatements:H302-Harmfulifswallowed |
| CiteThisProduct | Dimethyloxaloylglycine(DMOG)(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-382) |
BIOLOGicalDescription
| AlternativeNames | DMOG,N-(Methoxyoxoacetyl)-glycinemethylester |
| ResearchAreas | CellSignaling |
| PubChemID | 560326 |
| ScientificBackground | DMOGisacellpermeableprolyl-4-hydroxylaseinhibitorwhichupregulatesHIFactivity.HIFactivationstimulatesangiogenesisinseveraldifferentmodels.DMOGalsoinhibitsFIH(FactorInhibitingHIF),anasparaginylhydroxylase,whichenhancestheHIFresponse.Itisactiveinvivoandattenuatesmyocardialinjuryinarabbitischemiareperfusionmodel(20mg/kg).Isexpectedtoactpro-angiogenic. |
| References | 1.GrozingerC.M.,etal.(2001)J.Biol.Chem.276(42):38837-43. 2.MaiA.,etal.(2005)J.Med.Chem.48(24):7789-95. 3.KahyoT.,etal.(2008)J.Pharmacol.Sci.108(3):364-71. 4.Jung-HynesB.,etal.(2009)J.Biol.Chem.284(6):3823-32. |
ProductImages
ChemicalstructureofDimethyloxaloylglycine(DMOG)(SIH-382),aProlyl-4-hydroxylaseinhibitor.CAS#:89464-63-1.MolecularFormula:C6H9NO5.MolecularWeight:175.1g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
