StressMarq/Dasatinib/SIH-440-5MG/5-mg
商品编号：
SIH-440-5MG
市场价：
¥1240.00
美元价：
744.00
产品分类：
电泳缓冲液
公司分类：
Electrophoretic_buffer
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Dasatinib |
| Description | Kinaseinhibitor |
| Purity | >98% |
| CASNo. | 302962-49-8 |
| MolecularFormula | C22H26ClN7O2S |
| MolecularWeight | 488.0 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(200mg/ml),ethanol(verypoorly),andwater(verypoorly) |
| Source | Synthetic |
| Appearance | Crystallinesolid |
| SMILES | C1=C(SC(=N1)NC2=CC(=NC(=N2)C)N3CCN(CC3)CCO)C(=O)NC4=C(C=CC=C4Cl)C |
| InChI | InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h4-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27) |
| InChIKey | ZBNZXTGUTAYRHI-UHFFFAOYSA-N |
| SafetyPhrases | Classification:AcuteToxicity:Oral,Category3ToxicToReproduction,Category1BTargetOrganSystemicToxicity(singleexposure),Category2TargetOrganSystemicToxicity(repeatedexposure),Category2SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H301:Toxicifswallowed.H360:Maydamagefertilityortheunbornchild.H370:Causesdamagetoorgans{uterus,testicles,ovaries}.H373:Maycausedamageto{uterus,testicles,ovaries}throughprolongedorrepeatedexposure.Precautionarystatements:P264:Wash{hands}thoroughlyafterhandling.P201:Obtainspecialinstructionsbeforeuse.P202:Donothandleuntilallsafetyprecautionshavebeenreadandunderstood.P281:Usepersonalprotectiveequipmentasrequired.P260:Donotbreathe{dust/fume/gas/mist/vapours/spray}.P301+310:IFSWALLOWED:ImmediatelycallaPOISONCENTERordoctor/physician.P330:Rinsemouth.P308+313:IFexposedorconcerned:Getmedicalattentiodvice.P312:Calla{POISONCENTER/doctor/...}ifyoufeelunwell.P314:Getmedicalattentiodviceifyoufeelunwell. |
| CiteThisProduct | Dasatinib(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-440) |
BIOLOGicalDescription
| AlternativeNames | N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 3062316 |
| ScientificBackground | DasatinibisadualSrcandAblkinaseinhibitorwith∼325timesmorepotencyagainstBCR-ABLthanimatinib.Specifically,itinhibitsautophosphorylationandsubstratephosphorylationinaconcentration-dependentmanner. |
| References | 1.BenjaminiO.,etal.(2014)Am.J.Hematology.89(3):282–287. |
ProductImages
ChemicalstructureofDasatinib(SIH-440),aSrcandBcr/Ablkinaseinhibitor.CAS#:302962-49-8.MolecularFormula:C22H26ClN7O2S.MolecularWeight:488g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
