StressMarq/Cytochalasin D/SIH-241-5MG/5-mg
商品编号：
SIH-241-5MG
市场价：
¥6300.00
美元价：
3780.00
产品分类：
电泳缓冲液
公司分类：
Electrophoretic_buffer
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | CytochalasinD |
| Description | Actinpolymerizationinhibitor |
| Purity | >98%(TLC);NMR(Conforms) |
| CASNo. | 22144-77-0 |
| MolecularFormula | C30H37NO6 |
| MolecularWeight | 507.63 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto10mMinethanolandto50mMinDMSO |
| Source | Synthetic |
| Appearance | WhiteSolid |
| SMILES | C[[email protected]]1C/C=C/[[email protected]]2[[email protected]@H](C(=C)[[email protected]]([[email protected]@H]3[[email protected]@]2([[email protected]@H](/C=C/[[email protected]](C1)C)OC(=O)C)C(=O)N[[email protected]]3CC4=CC=CC=C4)C)O |
| InChI | InChI=1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,3 |
| InChIKey | SDZRWUKZFQQKKV-BBXOWAOSSA-N |
| SafetyPhrases | Classification:Toxic.Maybeharmfulorfatalifinhaled,swallowedorabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionRiskPhrases:R62-PossIBLeriskofimpairedfertilityR68-PossibleriskofirreversibleeffectsHazardPhrases:H300-H361PrecautionaryPhrases:P264-P281-P301+P310 |
| CiteThisProduct | CytochalasinD(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-241) |
BIOLOGicalDescription
| AlternativeNames | (3S,3aR,4S,6S,6aR,7E,10S,12S,13E,15R,15aR)-3-Benzyl-6-hydroxy-4,10,12-trimethyl-5-methylene-1-oxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-ylacetate,ZygosporinA |
| ResearchAreas | Cancer,Apoptosis |
| PubChemID | 5458428 |
| ScientificBackground | CytochalasinshavetheABIlitytobindtoactinfilamentsandblockpolymerizationandelongationofactin.Asaresult,theycanchangecellularmorphology,inhibitcellularprocessesandcausecellstoundergoapoptosis(1).CytochalasinDinparticularcaninhibitproteinsynthesis(2). |
| References | 1. HaidleA.,andMyersA.(2004)ProcNatlAcadSci.101(33):12048-12053. 2.Ornellesetal.,(1986)MolCellBiol.6(5):1650-1662. |
ProductImages
ChemicalstructureofCytochalasinD(SIH-241),aDisruptsactinfilaments.CAS#:22144-77-0.MolecularFormula:C30H37NO6.MolecularWeight:507.63g/mol.
ProductCitations(3)
OtherCitations
M2BPinhibitsHIV-1virionproductioninavimentinfilaments-dependentmanner.
Wang,Q.,Zhang,X.,Han,Y.,Wang,X.andGao,G.(2016)SciRep.6:32736.
PubMedID:27604950Applications:Celltreatment
PlasmacontributestotheantimicrobialactivityofwholebloodagainstMycobacteriumtuberculosis.
López-Medrano,R.(2016)InnateImmun.22(7):557-66.
PubMedID:27554054Applications:Invitroinhibition
BlebformationisinducedbyalkalinebutnotacidicpHinestrogenreceptorsilencedbreastcancercells.
Khajah,M.A.,Mathew,P.M.,Alam-Eldin,N.S.andLuqmani,Y.A.(2015)IntJOncol.46(4):1685-98.
PubMedID:25672508Applications:Invitroinhibition
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
