StressMarq/Cyclosporine/SIH-201-100MG/100-mg
商品编号：
SIH-201-100MG
市场价：
¥6400.00
美元价：
3840.00
产品分类：
电泳缓冲液
公司分类：
Electrophoretic_buffer
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Cyclosporine |
| Description | Immunosuppressant |
| Purity | >99% |
| CASNo. | 59865-13-3 |
| MolecularFormula | C62H111N11O12 |
| MolecularWeight | 1202.63 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto100mMinDMSO,50mMinethanol |
| Source | Synthetic |
| Appearance | WhiteSolid |
| SMILES | CC[[email protected]]1C(=O)N(CC(=O)N([[email protected]](C(=O)N[[email protected]](C(=O)N([[email protected]](C(=O)N[[email protected]](C(=O)N[[email protected]@H](C(=O)N([[email protected]](C(=O)N([[email protected]](C(=O)N([[email protected]](C(=O)N([[email protected]](C(=O)N1)[[email protected]@H]([[email protected]](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC( |
| InChI | InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45( |
| InChIKey | PMATZTZNYRCHOR-IMVLJIQESA-N |
| SafetyPhrases | Classification:Toxic.Maybeharmfulorfatalifinhaled,swallowedorabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS45-Incaseofaccidentorifyoufeelunwell,seekmedicaladviceimmediately(showthelabelwherepossIBLe)RiskPhrases:R20/21/22-Harmfulbyinhilation,incontactwithskinandifswallowedR45-MaycausecancerR62-PossibleriskofimpairedfertilityR68-PossibleriskofirreversibleeffectsHazardPhrases:H302-H350-H360PrecautionaryPhrases:P201-P308+P313 |
| CiteThisProduct | Cyclosporine(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-201) |
BIOLOGicalDescription
| AlternativeNames | (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methyl-4-hexen-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone,CyclosporinA |
| ResearchAreas | Cancer,Apoptosis |
| PubChemID | 5284373 |
| ScientificBackground | CyclosporinAisahydrophobiccyclicpeptide,andisapotentimmune-suppressantandantifungal.ItactsviaitsABIlitytobindtoafamilyofintracellularproteins(1).TheimmunosuppressantactionismediatedbythecomplexCyclosporin-A-cyclophilinthatspecificallyinhibitstheCa2+/calmodulin-dependentserine-threonine-proteinphosphatase-2B.ThisisturninhibitscalcineurinandpromotesdephosphorylationoftranscriptionfactorNF-ATandT-cellactivation(2). |
| References | 1.HeitmanJ.,etal.(1992)NewBiol.4:448. 2.GanongW.F.ReviewofMedicalPhysiology,22ndedition.LangeMedicalBooks,Chapter27,Page530. |
ProductImages
ChemicalstructureofCyclosporine(SIH-201),aInhibitsmitochondrialpermeabilityporeopening.CAS#:59865-13-3.MolecularFormula:C62H111N11O12.MolecularWeight:1202.63g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
