StressMarq/Cyclopamine/SIH-226-5MG/5-mg
商品编号：
SIH-226-5MG
市场价：
¥5000.00
美元价：
3000.00
产品分类：
电泳缓冲液
公司分类：
Electrophoretic_buffer
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Cyclopamine |
| Description | Hedgehogsignalingblocker |
| Purity | >98% |
| CASNo. | 4449-51-8 |
| MolecularFormula | C27H41NO2 |
| MolecularWeight | 434.15 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto5mMinethanol |
| Source | Synthetic |
| Appearance | WhiteSolid |
| SMILES | C[[email protected]]1C[[email protected]@H]2[[email protected]]([[email protected]]([[email protected]]3(O2)CC[[email protected]]4[[email protected]@H]5CC=C6C[[email protected]](CC[[email protected]@]6([[email protected]]5CC4=C3C)C)O)C)NC1 |
| InChI | InChI=1S/C27H41NO2/c1-15-11-24-25(28-14-15)17(3)27(30-24)10-8-20-21-6-5-18-12-19(29)7-9-26(18,4)23(21)13-22(20)16(27)2/h5,15,17 |
| InChIKey | QASFUMOKHFSJGL-LAFRSMQTSA-N |
| SafetyPhrases | Classification:Harmful.Maybeharmfulifinhaled,swallowedorabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionRiskPhrases:R62-PossIBLeriskofimpairedfertility |
| CiteThisProduct | Cyclopamine(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-226) |
BIOLOGicalDescription
| AlternativeNames | (3β,22S,23R)-17,23-Epoxyveratraman-3-ol |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,HedgehogPathwayBlocker |
| PubChemID | 442972 |
| ScientificBackground | CyclopamineisahedgehogsignalingpathwayinhibitorthatinfluencesthebalancebetweentheactiveandinactiveformsoftheSmoothenedprotein(1).Itisbeinginvestigatedasatreatmentagentinbasalcellcarcinoma,medulloblastomaandrhaBDomyosarcoma(1,2). |
| References | 1.BeachyP.A.,etal.(2000)Nature.406(6799):1005-1009. 2.YauchR.L.,etal.(2009)Science.326(5952):572-574. |
ProductImages
ChemicalstructureofCyclopamine(SIH-226),aInhibitshedgehogsignaling.CAS#:4449-51-8.MolecularFormula:C27H41NO2.MolecularWeight:434.15g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
