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当前位置: 首页 > 产品中心 > Electrophoretic_buffer > StressMarq/Cyclopamine/SIH-226-1MG/1-mg
商品详细StressMarq/Cyclopamine/SIH-226-1MG/1-mg
StressMarq/Cyclopamine/SIH-226-1MG/1-mg
StressMarq/Cyclopamine/SIH-226-1MG/1-mg
商品编号: SIH-226-1MG
市场价: ¥1240.00
美元价: 744.00
产地: 美国(厂家直采)
公司:
产品分类: 电泳缓冲液
公司分类: Electrophoretic_buffer
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameCyclopamine
Description

Hedgehogsignalingblocker

Purity>98%
CASNo.4449-51-8
MolecularFormulaC27H41NO2
MolecularWeight434.15

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleto5mMinethanol
SourceSynthetic
AppearanceWhiteSolid
SMILESC[[email protected]]1C[[email protected]@H]2[[email protected]]([[email protected]]([[email protected]]3(O2)CC[[email protected]]4[[email protected]@H]5CC=C6C[[email protected]](CC[[email protected]@]6([[email protected]]5CC4=C3C)C)O)C)NC1
InChIInChI=1S/C27H41NO2/c1-15-11-24-25(28-14-15)17(3)27(30-24)10-8-20-21-6-5-18-12-19(29)7-9-26(18,4)23(21)13-22(20)16(27)2/h5,15,17
InChIKeyQASFUMOKHFSJGL-LAFRSMQTSA-N
SafetyPhrasesClassification:Harmful.Maybeharmfulifinhaled,swallowedorabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionRiskPhrases:R62-PossIBLeriskofimpairedfertility
CiteThisProductCyclopamine(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-226)

BIOLOGicalDescription

AlternativeNames(3β,22S,23R)-17,23-Epoxyveratraman-3-ol
ResearchAreasCancer,Apoptosis,CancerGrowthInhibitors,HedgehogPathwayBlocker
PubChemID442972
ScientificBackgroundCyclopamineisahedgehogsignalingpathwayinhibitorthatinfluencesthebalancebetweentheactiveandinactiveformsoftheSmoothenedprotein(1).Itisbeinginvestigatedasatreatmentagentinbasalcellcarcinoma,medulloblastomaandrhaBDomyosarcoma(1,2).
References1.BeachyP.A.,etal.(2000)Nature.406(6799):1005-1009.
2.YauchR.L.,etal.(2009)Science.326(5952):572-574.

ProductImages

<p>Chemical structure of Cyclopamine (SIH-226), a Inhibits hedgehog signaling. CAS #: 4449-51-8. Molecular Formula: C27H41NO2. Molecular Weight: 434.15 g/mol.</p>

ChemicalstructureofCyclopamine(SIH-226),aInhibitshedgehogsignaling.CAS#:4449-51-8.MolecularFormula:C27H41NO2.MolecularWeight:434.15g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。