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当前位置: 首页 > 产品中心 > Electrophoretic_buffer > STRESS MARQ/Cpn10蛋白质/SPR-310C/2x100-微克
商品详细STRESS MARQ/Cpn10蛋白质/SPR-310C/2x100-微克
STRESS MARQ/Cpn10蛋白质/SPR-310C/2x100-微克
STRESS MARQ/Cpn10蛋白质/SPR-310C/2x100-微克
商品编号: SPR-310C
市场价: ¥12260.00
美元价: 7356.00
产地: 美国(厂家直采)
公司:
产品分类: 电泳缓冲液
公司分类: Electrophoretic_buffer
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameCpn10Protein
Description

HumanRecombinantCpn10Protein

ApplicationsWB,SDS-PAGE
ConcentrationLot/batchspecific.Seeincludeddatasheet.
ConjugatesNotag

Properties

StorageBuffer20mMTris,pH7.5,0.3MNaCl,10%glycerol,1mMDTT
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationMulti-StepPurified
Specificity~10kDa
CiteThisProductHumanRecombinantCpn10Protein(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SPR-310)
CertificateofAnalysisThisproducthasbeencertified>90%pureusingSDS-PAGEanalysis.

BIOLOGicalDescription

AlternativeNames10kDaChaperoninProtein,Chaperonin10Protein,Cpn10Protein,EPFProtein,GROESProtein,HeatShock10kDprotein1Protein,HSP10Protein,HSPE1Protein
ResearchAreasCancer,HeatShock
CellularLocalizationMitochondrionMatrix
AccessionNumberNM_002157.2
GeneID3336
SwissProtP61604
ScientificBackgroundChaperonin10,otherwiseknownasCpn10,(groESinE.coli)makeupafamilyofsmallheartshockproteinswithanapproximatemolecularmassof10kDa(HSP10s).Cpn10actsasaco-chaperoneandinteractswiththeHSP60familytopromoteproperfoldingofpolypeptides.Cpn10andCpn60bothexhibitsevenfoldaxisofsymmetryandfunctionasateamintheproteinfoldingandassemblyprocess(1).Cpn10hasbeenlocatedinhumanplatelets,butisalsopresentinhumanmaternalserum(2,3).IthasbeenreportedthathumanCpn10isidenticalwithearlypregnancyfactor,whichisinvolvedincontrolovercellgrowthanddevelopment.ThisidentificationsuggestthatCpn10mayactlikeahormoneinstressfulsituationssuchaspregnancy(4).
References1.Velez-GranellC.S.,etal.(1994)JofCellScience.107(3):539-549.
2.MortonH.,HeghV.,andClunieG.J.A.(1974)Nature(London)249:459-460.
3.CavanaghA.C.,andMortonH.(1994)Eur.J.Biochem.222:551-560.
4.MintoM.,etal.(1998)MolecularCellResearch.1403(2):151-157.

ProductImages

<p>SDS-PAGE of 10kDa human Cpn10 protein (SPR-310).</p>

SDS-PAGEof10kDahumanCpn10protein(SPR-310).

ProductCitations(1)

OtherCitations

Monocytecytokinesynthesisinresponsetoextracellularcellstressproteinssuggeststheseproteinsexhibitnetworkbehaviour.

Kaiser,F.,Steptoe,A.,Thompson,S.andHenderson,B.(2014)CellStressChaperones.19(1):135-44.

PubMedID:23775284Applications:FunctionalAssay

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。