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当前位置: 首页 > 产品中心 > Electrophoretic_buffer > StressMarq/Chloroquine diphosphate/SIH-405-1G/1-g
商品详细StressMarq/Chloroquine diphosphate/SIH-405-1G/1-g
StressMarq/Chloroquine diphosphate/SIH-405-1G/1-g
StressMarq/Chloroquine diphosphate/SIH-405-1G/1-g
商品编号: SIH-405-1G
市场价: ¥580.00
美元价: 348.00
产地: 美国(厂家直采)
公司:
产品分类: 电泳缓冲液
公司分类: Electrophoretic_buffer
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameChloroquinediphosphate
Description

Autophagyinhibitor

Purity>98%
CASNo.50-63-5
MolecularFormulaC18H26ClN3·2H3PO4
MolecularWeight515.86

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleto100mMinwater.
SourceSynthetic
AppearanceBeigeSolid
SMILESC1=CC(=CC2=C1C(=CC=N2)NC(CCCN(CC)CC)C)Cl.O=[P](O)(O)O.O=[P](O)(O)O
InChIInChI=1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4)
InChIKeyQKICWELGRMTQCR-UHFFFAOYSA-N
SafetyPhrasesClassification:NotWHMIScontrolled.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.
CiteThisProductChloroquinediphosphate(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-405)

BIOLOGicalDescription

AlternativeNamesN4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediaminediphosphatesalt
ResearchAreasCancer,Autophagy
PubChemID64927
ScientificBackgroundChloroquinediphosphatewasoriginallydevelopedasatreatmentagainstmalaria.Ithassincebeenimplicatedincancerresearchasitinhibitscellgrowthandinducescelldeathinanumberofcancercelllines.Chloroquinealsoinhibitsautophagybyspecificallyblockingacidificationofthelysosomeswhichfusewithautophagosomes.Thisconsequentlypreventsthedegradationofmaterials.
References1.JiangP.D.,etal.(2010)BiomedPharmacother.64(9):609-14.
2.EggerM.E.,etal.(2013)JSurgRes.184(1):274-81.

ProductImages

<p>Chemical structure of Chloroquine diphosphate (SIH-405), a Autophagy inhibitor. CAS #: 50-63-5. Molecular Formula: C18H26ClN3·2H3PO4. Molecular Weight: 515.86 g/mol.</p>

ChemicalstructureofChloroquinediphosphate(SIH-405),aAutophagyinhibitor.CAS#:50-63-5.MolecularFormula:C18H26ClN3·2H3PO4.MolecularWeight:515.86g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。