StressMarq/Chloroquine diphosphate/SIH-405-1G/1-g
商品编号:
SIH-405-1G
市场价:
¥580.00
美元价:
348.00
产品分类:
电泳缓冲液
公司分类:
Electrophoretic_buffer
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Overview:
ProductName | Chloroquinediphosphate |
Description | Autophagyinhibitor |
Purity | >98% |
CASNo. | 50-63-5 |
MolecularFormula | C18H26ClN3·2H3PO4 |
MolecularWeight | 515.86 |
Properties
StorageTemperature | -20ºC |
ShippingTemperature | ShippedAmbient |
ProductType | Inhibitor |
Solubility | Solubleto100mMinwater. |
Source | Synthetic |
Appearance | BeigeSolid |
SMILES | C1=CC(=CC2=C1C(=CC=N2)NC(CCCN(CC)CC)C)Cl.O=[P](O)(O)O.O=[P](O)(O)O |
InChI | InChI=1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4) |
InChIKey | QKICWELGRMTQCR-UHFFFAOYSA-N |
SafetyPhrases | Classification:NotWHMIScontrolled.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection. |
CiteThisProduct | Chloroquinediphosphate(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-405) |
BIOLOGicalDescription
AlternativeNames | N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediaminediphosphatesalt |
ResearchAreas | Cancer,Autophagy |
PubChemID | 64927 |
ScientificBackground | Chloroquinediphosphatewasoriginallydevelopedasatreatmentagainstmalaria.Ithassincebeenimplicatedincancerresearchasitinhibitscellgrowthandinducescelldeathinanumberofcancercelllines.Chloroquinealsoinhibitsautophagybyspecificallyblockingacidificationofthelysosomeswhichfusewithautophagosomes.Thisconsequentlypreventsthedegradationofmaterials. |
References | 1.JiangP.D.,etal.(2010)BiomedPharmacother.64(9):609-14. 2.EggerM.E.,etal.(2013)JSurgRes.184(1):274-81. |
ProductImages
ChemicalstructureofChloroquinediphosphate(SIH-405),aAutophagyinhibitor.CAS#:50-63-5.MolecularFormula:C18H26ClN3·2H3PO4.MolecularWeight:515.86g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。