StressMarq/Celastrol/SIH-333-10MG/10-mg
商品编号：
SIH-333-10MG
市场价：
¥1440.00
美元价：
864.00
产品分类：
电泳缓冲液
公司分类：
Electrophoretic_buffer
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Celastrol |
| Description | Proteasomeinhibitor |
| Purity | >98% |
| CASNo. | 34157-83-0 |
| MolecularFormula | C29H38O4 |
| MolecularWeight | 450.6 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solublein45mg/mlDMSO,30mg/mlEthanol |
| Source | Synthetic |
| Appearance | RedPowder |
| SMILES | CC1=C(C(=O)C=C2C1=CC=C3[[email protected]]2(CC[[email protected]@]4([[email protected]@]3(CC[[email protected]@]5([[email protected]]4C[[email protected]](CC5)(C)C(=O)O)C)C)C)C)O |
| InChI | InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1 |
| InChIKey | KQJSQWZMSAGSHN-JJWQIEBTSA-N |
| SafetyPhrases | Classification:Toxic-ToxicMaterialCausingImmediateandSeriousToxicEffectsSafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-AvoidcontactwithskinandeyesHazardStatements:H301–ToxicifswallowedPrecautionaryStatements:P301+P31–IfSwallowed,immediatelycallaPOISONCENTERordoctor. |
| CiteThisProduct | Celastrol(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-333) |
BIOLOGicalDescription
| AlternativeNames | 3-hydroxy-9β,13α-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oicacid,10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-picene-2-carboxylicacid,Tripterin |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,ProteasomeInhibitors |
| PubChemID | 122724 |
| ScientificBackground | Displayspotentantioxidantandanti-inflammatoryactivity.InhibitsNFB(IC50=270nM).Itinducesheatshockresponseandcytoprotectioninvariouscells.Itinhibits20Sproteasomechymotrypsinactivity(IC50=2.5M).Cellpermeable. |
| References | 1.SethiG.,etal.(2007)Blood109:2727. 2.WesterheideS.D.,etal.(2004)J.Biol.Chem.279:56053. 3.YangH.,etal.(2006)CancerRes.66:4758. |
ProductImages
ChemicalstructureofCelastrol(SIH-333),aProteasomeinhibitor.CAS#:34157-83-0.MolecularFormula:C29H38O4.MolecularWeight:450.6g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
