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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-CDC25C Antibody/SPC-1113D/100-µl
商品详细StressMarq/Anti-CDC25C Antibody/SPC-1113D/100-µl
StressMarq/Anti-CDC25C Antibody/SPC-1113D/100-µl
StressMarq/Anti-CDC25C Antibody/SPC-1113D/100-µl
商品编号: SPC-1113D
市场价: ¥5900.00
美元价: 3540.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name CDC25C Antibody
Description

Rabbit Anti-Human CDC25C Polyclonal

Species Reactivity Human, Mouse
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen Synthetic peptide of human CDC25C (AA275-290)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 53.365 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-1113, RRID: AB_2710433
Certificate of Analysis A 1:250 dilution of SPC-1113 was sufficient for detection of CDC25C in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names CDC 25 antibody, Cdc 25C antibody, CDC25 antibody, CDC25C antibody, Cell division cycle 25 homolog C antibody, Cell division cycle 25C antibody, Dual specificity phosphatase Cdc25C antibody, M phase inducer phosphatase 3 antibody, Mitosis inducer CDC25 antibody, MPIP3 antibody, MPIP3_HUMAN antibody, Phosphotyrosine phosphatase antibody, PPP1R60 antibody
Cellular Localization Nucleus
Accession Number NP_001781
Gene ID 995
Swiss Prot P30307
Scientific Background The Cdc2/cyclin B enzyme, involved in regulation of mitosis in eukaryotic cells, is subject to multiple levels of control. Among these, the regulation of the catalytic subunit by Tyrosine phosphorylation is the best understood. Tyrosine phosphorylation inhibits the Cdc2/cyclin B complex, while Tyrosine dephosphorylation, which occurs at the onset of mitosis, directly activates the pre-MPH complex. The Cdc25 gene serves as a rate-limiting mitotic activator, apparently due to its action as the Cdc2 Tyrosine phosphatase. In the absence of Cdc25, Cdc2 accumulates in a Tyrosine phosphorylated state. In addition, Cdc25 proteins from a variety of species have been shown to share a low degree of sequence similarity with other Tyrosine phosphatases. The Cdc25 gene family consists of at least three members that share approximately 40% identity in their most conserved carboxy-terminal sequences.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。