STRESS MARQ/CCT241161/SIH-186-10MG/10MG
商品编号：
SIH-186-10MG
市场价：
¥11200.00
美元价：
6720.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | CCT241161 |
| Description | RAFInhibitor |
| Purity | >98% |
| CASNo. | 1163719-91-2 |
| MolecularFormula | C28H27N7O3S |
| MolecularWeight | 541.63 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | BlueIceor4ºC |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO |
| Source | Synthetic |
| Appearance | WhiteSolid |
| SMILES | CC(C)(C)C1=NN(C2=CC=CC=C2)C(NC(NC(C(SC)=C3)=CC=C3OC4=C5C(NC(C=N5)=O)=NC=C4)=O)=C1 |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection |
| CiteThisProduct | CCT241161(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-186) |
BIOLOGicalDescription
| AlternativeNames | 1-(3-(tert-butyl)-1-phenyl-1H-pyrazol-5-yl)-3-(2-(methylthio)-4-((3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yl)oxy)phenyl)urea |
| ResearchAreas | Cancer,Apoptosis |
| ScientificBackground | CCT241161,apan-RAF/SFKinhibitorisactiveagainsttreatment-naiveBRAFandNRASmutanttumors.ItisactiveintumorsfrompatientswhodevelopedresistancetoBRAF-selectiveinhibitorsandaBRAFplusMEKinhibitorcombination.IC500.03µMand0.01µMforBRAFkinaseandSRCkinaserespectively. |
| References | 1.Girotti,M.R.,etal.(2015)CancerCell27.1:85-96. |
ProductImages
ChemicalstructureofCCT241161(SIH-186),aRAFInhibitor.CAS#:1163719-91-2.MolecularFormula:C28H27N7O3S.MolecularWeight:541.63g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
