STRESS MARQ/鼠尾草酸/SIH-362-10MG/10MG
商品编号：
SIH-362-10MG
市场价：
¥980.00
美元价：
588.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Carnosicacid |
| Description | PPARγactivator |
| Purity | >95%(HPLC);NMR(Conforms) |
| CASNo. | 07-09-50 |
| MolecularFormula | C20H28O4 |
| MolecularWeight | 332.43 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Activator |
| Solubility | SolubleinDMSO(50mg/ml) |
| Source | Synthetic |
| Appearance | Offwhitetoyellowsolid |
| SMILES | CC(C)C1=C(C(=C2C(=C1)CC[[email protected]@H]3[[email protected]@]2(CCCC3(C)C)C(=O)O)O)O |
| InChI | InChI=1S/C20H28O4/c1-11(2)13-10-12-6-7-14-19(3,4)8-5-9-20(14,18(23)24)15(12)17(22)16(13)21/h10-11,14,21-22H,5-9H2,1-4H3,(H,23,24)/t14-,20+/m0/s1 |
| InChIKey | QRYRORQUOLYVBU-VBKZILBWSA-N |
| SafetyPhrases | Classification:Caution-Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-Avoidcontactwithskinandeyes |
| CiteThisProduct | Carnosicacid(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-362) |
BIOLOGicalDescription
| AlternativeNames | (4aR,10aS)-5,6-Dihydroxy-7-isopropyl-1,1-dimethyl-1,3,4,9,10,10a-hexahydro-2H-phenanthrene-4a-carboxylicacid |
| ResearchAreas | Cancer,Apoptosis |
| PubChemID | 65126 |
| ScientificBackground | CarnosicacidisabenzenediolABIetanediterpenenaturallyextractedfromrosemary(Rosmarinusofficinalis)andsage(Salivaofficinalis).ItisapotentantioxidantthatinhibitsNADHorNADPHinducedlipidperoxidationbyactingasafreerADIcalscavenger(1).Ithasbeenfoundtoincreasecellularlevelsofglutathione(GSH)andprevent6-hydroxydopamine-inducedcelldeathinSH-SY5Ycells(2).Carnosicacid-stimulationofGSHalsoinhibitsadipocytedifferentiation(3).Ithasalsobeenfoundtoinduceapoptosis(4)andinhibittheproliferationandmigrationofvarioustumorcelllines(5). |
| References | 1.SchwarzK.,TernesW.(1992)ZeitschriftfürLebensmittel-Untersuchungund–Forschung.195(2):99-103. 2.ChenJ.H.,etal.Chem.(2012)Res.Toxicol25:1893. 3.TakahashiT.,etal.(2009)Biochem.Biophys.Res.Commun.382:549. 4.KarS.,etal.(2012)Apoptosis.17:1735. 5.BarniM.V.,etal.(2012)Oncol.Rep.27:1041. |
ProductImages
ChemicalstructureofCarnosicacid(SIH-362),aREDOX&GSHinduction.CAS#:3650-09-7.MolecularFormula:C20H28O4.MolecularWeight:332.43g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
