StressMarq/Camptothecin/SIH-242-100MG/100-mg
商品编号：
SIH-242-100MG
市场价：
¥740.00
美元价：
444.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Camptothecin |
| Description | TopoisomeraseIinhibitor |
| Purity | >98% |
| CASNo. | 04-03-89 |
| MolecularFormula | C20H16N2O4 |
| MolecularWeight | 348.36 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto5mMinDMSO |
| Source | Synthetic |
| Appearance | Yellowsolid |
| SMILES | CC[[email protected]@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O |
| InChI | InChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h4-8,25H,2,9-10H2,1 |
| InChIKey | VSJKWCGYPAHWDS-FQEVSTJZSA-N |
| SafetyPhrases | Classification:Toxic.Maybeharmfulorfatalifinhaled,swallowedorabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS45-Incaseofaccidentorifyoufeelunwell,seekmedicaladviceimmediately(showthelabelwherepossIBLe)RiskPhrases:R23/24/25-Toxicbyinhalation,incontactwithskinandifswallowedR46-MaycauseheritablegeneticdamageHazardPhrases:H302 |
| CiteThisProduct | Camptothecin(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-242) |
BIOLOGicalDescription
| AlternativeNames | (4S)-4-Ethyl-4-hydroxy-1H-pyrano[3",4":6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione |
| ResearchAreas | Cancer,Apoptosis |
| PubChemID | 24360 |
| ScientificBackground | CamptothecinisacytotoxicquinolinealkaloidwhichinhibitstheDNAenzymetopoisomeraseI.ItbindstothetopoIandDNAcomplex,resultinginatertiarycomlexwhichstABIlizesit.Thispreventsre-ligationandthereforecausesDNAdamagewhichresultsinapoptosis(1-3).Ithasshowedremarkableanti-canceractivityinclinicaltrials. |
| References | 1.AdamsD.J.,etal.(2005)CancerChemandPharm.57(2):145-154. 2.RedinboM.R.,StewartL.,KuhnP.,ChampouxJ.J.andHolW.G.J.(1998)Science.279:1504-1513. 3.PommierY.,etal.(2003)MutatRes.532:173-203. |
ProductImages
ChemicalstructureofCamptothecin(SIH-242),aTopoisomeraseIinhibitor.CAS#:7689-03-4.MolecularFormula:C20H16N2O4.MolecularWeight:348.36g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
