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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/抗CaMKIV抗体(pThr200)/SPC-932D-A700/100-µl
商品详细StressMarq/抗CaMKIV抗体(pThr200)/SPC-932D-A700/100-µl
StressMarq/抗CaMKIV抗体(pThr200)/SPC-932D-A700/100-µl
StressMarq/抗CaMKIV抗体(pThr200)/SPC-932D-A700/100-µl
商品编号: SPC-932D-A700
市场价: ¥6840.00
美元价: 4104.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name CaMKIV Antibody (pThr200)
Description

Rabbit Anti-Human CaMKIV (pThr200) Polyclonal

Species Reactivity Human
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A phospho-specific peptide corresponding to residues surrounding Thr200 of human CaMKIV (AA197-203)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 51.926 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-932, RRID: AB_2707175
Certificate of Analysis A 1:250 dilution of SPC-932 was sufficient for detection of CaMKIV (pThr200) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names Brain Ca++-calmodulin dependent protein kinase type IV Antibody, Calcium / calmodulin dependent protein kinase type 4 catalytic chain Antibody, Calcium/calmodulin dependent protein kinase IV Antibody, CAM kinase 4 Antibody, CAM kinase GR Antibody, CAM kinase IV Antibody, CaMK IV Antibody, KCC4_HUMAN Antibody
Research Areas Cell Signaling, Chromatin Modifying Enzymes, Epigenetics and Nuclear Signaling, Neuroscience, Neurotransmitter Receptors
Cellular Localization Cytoplasm, Nucleus
Accession Number NP_001735
Gene ID 814
Swiss Prot Q16566
Scientific Background CAMKIV is a calcium/calmodulin-dependent protein-serine/threonine kinase. It is implicated in immune response, inflammation, memory consolidation, positive selection of T lymphocytes, cytokine production, regulation in neurons and male germ cells, survival and differentiation of osteoblasts and dendritic cells. It regulates many transcription activators such as CREB1, and JUN. It can also activate MAPK pathway through phosphorylation of ELK1 and ATF2.

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 ATTO 700
Overview:

  • High fluorescence yield
  • Excellent thermal and photostability
  • Quenched by electron donors
  • Very hydrophilic
  • Good solubility in polar solvents
  • Zwitterionic dye
  • Molar Mass: 575 g/mol

ATTO 700 Datasheet

 ATTO 700 Fluorophore Absorption and Emission SpectrumOptical Properties:

λex = 700 nm

λem = 719 nm

εmax = 1.25×105

Φf = 0.25

τfl = 1.6 ns

Brightness = 31.3

Laser = 676 nm

Filter set = Cy®5.5

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。