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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-CaMKI Antibody (pThr177)/SPC-930D/100-µl
商品详细StressMarq/Anti-CaMKI Antibody (pThr177)/SPC-930D/100-µl
StressMarq/Anti-CaMKI Antibody (pThr177)/SPC-930D/100-µl
StressMarq/Anti-CaMKI Antibody (pThr177)/SPC-930D/100-µl
商品编号: SPC-930D
市场价: ¥5900.00
美元价: 3540.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name CaMKI Antibody (pThr177)
Description

Rabbit Anti-Human CaMKI (pThr177) Polyclonal

Species Reactivity Human
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A phospho-specific peptide corresponding to residues surrounding Thr177 of human CaMK1 (AA174-180)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 41.337 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-930, RRID: AB_2707139
Certificate of Analysis A 1:250 dilution of SPC-930 was sufficient for detection of CaMKI (pThr177) in 10 µg of human brain lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names Calcium / calmodulin dependent protein kinase type 1 Antibody, CaM K1 Antibody, CaM kinase 1 alpha Antibody, CaM-KI Antibody, CaMK1 alpha Antibody, CaMKI-alpha Antibody, KCC1A_HUMAN Antibody
Research Areas Cardiovascular System, Cell Signaling, Heart, Hypertrophy, Neuroscience, Neurotransmitter Receptors
Cellular Localization Cytoplasm, Nucleus
Accession Number NP_003647
Gene ID 8536
Swiss Prot Q14012
Scientific Background Calcium / calmodulin-dependent kinases (CaMKs) are a subfamily of the serine/threonine protein kinase family that includes CaMKI, CaMKII, and CaMKIV. There have been identified multiple substrates for CaMKI, including synapsin 1, synapsin 2, CREB, and CFTR, and its activation is dependent upon phosphorylation of Thr 177 by CaMK kinase (CaMKK). Studies suggest that CaMKI plays an important role in retinal function and its expression is regulated by light stimulation.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。