StressMarq/C16/SIH-498-25MG/25-mg
商品编号：
SIH-498-25MG
市场价：
¥5100.00
美元价：
3060.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | C16 |
| Description | PKRkinaseinhibitor |
| Purity | >98%(HPLC) |
| CASNo. | 608512-97-6 |
| MolecularFormula | C13H8N4OS |
| MolecularWeight | 268.3 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO12mg/ml |
| Source | Synthetic |
| Appearance | Solid |
| SMILES | C1=CC2=C(C3=C1NC(=O)/C3=CC4=CNC=N4)SC=N2 |
| InChI | InChI=1S/C13H8N4OS/c18-13-8(3-7-4-14-5-15-7)11-9(17-13)1-2-10-12(11)19-6-16-10/h1-6H,(H,14,15)(H,17,18)/b8-3+ |
| InChIKey | VFBGXTUGODTSPK-FPYGCLRLSA-N |
| SafetyPhrases | Classification:Chronicaquatictoxicity(Category4),H413SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H413Maycauselonglastingharmfuleffectstoaquaticlife.Precautionarystatements:P273Avoidreleasetotheenvironment.P501Disposeofcontents/containertoanapprovedwastedisposalplant. |
| CiteThisProduct | C16(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-498) |
BIOLOGicalDescription
| AlternativeNames | Imidazolo-oxindolePKRinhibitorC16,6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 67016828 |
| ScientificBackground | C16isaderivativeofimidazolo-oxindoleandinhibitsRNA-dependentproteinkinases(PKR).ItsinhibitioneffectonPKRisATP-bindingsitedirected.C16hasbeenshowntospecificallyinhibittheapoptoticPKR/eIF2asignalingpathway. |
| References | 1.CouturierJ.,etal.(2010)J.Biol.Chem.285(2):1272–1282. 2.JammiN.V.,WhitbyL.R.,&BealP.A.(2003)Biochem.Biophys.Res.Comm.308(1):50–57. |
ProductImages
ChemicalstructureofC16(SIH-498),aPKRkinaseinhibitor.CAS#:608512-97-6.MolecularFormula:C13H8N4OS.MolecularWeight:268.3g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
