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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-c-Kit Antibody (Ser821+ Tyr823)/SPC-1003D-A390/100-µl
商品详细StressMarq/Anti-c-Kit Antibody (Ser821+ Tyr823)/SPC-1003D-A390/100-µl
StressMarq/Anti-c-Kit Antibody (Ser821+ Tyr823)/SPC-1003D-A390/100-µl
StressMarq/Anti-c-Kit Antibody (Ser821+ Tyr823)/SPC-1003D-A390/100-µl
商品编号: SPC-1003D-A390
市场价: ¥6860.00
美元价: 4116.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name c-Kit Antibody (Ser821+ Tyr823)
Description

Rabbit Anti-Human c-Kit (Ser821+ Tyr823) Polyclonal

Species Reactivity Human
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A phospho-specific peptide corresponding to residues surrounding Ser821 and Tyr823 of human c-Kit (AA818-827)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 109.865 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-1003, RRID: AB_2708453
Certificate of Analysis A 1:250 dilution of SPC-1003 was sufficient for detection of c-Kit (Ser821+ Tyr823) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names C Kit Antibody, CD117 Antibody, Kit Antibody, KIT oncogene Antibody, Mast cell growth factor receptor Antibody, p145 c-kit Antibody, PBT Antibody, Proto oncogene tyrosine protein kinase Kit Antibody, SCF Receptor Antibody, soluble KIT variant 1 Antibody, Steel Factor Receptor Antibody, tyrosine protein kinase Kit Antibody, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog Antibody
Cellular Localization Cell membrane
Accession Number NP_000213
Gene ID 3815
Swiss Prot P10721
Scientific Background c-KIT is a receptor tyrosine kinase that plays an essential role in the regulation of cell survival and proliferation, especially hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and melanogenesis. Following activation by KITLG/SCF binding, it can activate the PLCG1, AKT1, RAS, and STAT pathways. Activation of PLCG1 can lead to increased calcium signalling. Mutations leading to constitutive kinase activity have been associated with gastrointestinal stromal tumour, testicular tumours, and acute myelogenous leukemia. The human proto-oncogene c-kit was first identified as the homolog of the feline sarcoma viral oncogene v-kit.

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  ATTO 390
Overview:

  • High fluorescence yield
  • Large Stokes-shift (89 nm)
  • Good photostability
  • Moderately hydrophilic
  • Good solubility in polar solvents
  • Coumarin derivate, uncharged
  • Low molar mass: 343.42 g/mol 

ATTO 390 Datasheet

ATTO 390 Fluorescent Dye Excitation and Emission SpectraOptical Properties:

λex = 390 nm

λem = 479 nm

εmax = 2.4×104

Φf = 0.90

τfl = 5.0 ns

Brightness = 21.6

Laser = 365 or 405 nm

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。