StressMarq/C-646/SIH-350-25MG/25-mg
商品编号：
SIH-350-25MG
市场价：
¥8660.00
美元价：
5196.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | C-646 |
| Description | HATinhibitor |
| Purity | >98%(TLC);NMR(Conforms) |
| CASNo. | 328968-36-1 |
| MolecularFormula | C24H19N3O6 |
| MolecularWeight | 445.4 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solublein10mg/mlDMSO |
| Source | Synthetic |
| Appearance | OrangeSolid |
| SMILES | CC1=CC(=C(C=C1C)[N+](=O)[O-])C2=CC=C(O2)/C=C/3C(=NN(C3=O)C4=CC=C(C=C4)C(=O)O)C |
| InChI | InChI=1S/C24H19N3O6/c1-13-10-20(21(27(31)32)11-14(13)2)22-9-8-18(33-22)12-19-15(3)25-26(23(19)28)17-6-4-16(5-7-17)24(29)30/h4-12H,1-3H3,(H,29,30)/b19-12+ |
| InChIKey | HEKJYZZSCQBJGB-XDHOZWIPSA-N |
| SafetyPhrases | Classification:Caution–Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-Avoidcontactwithskinandeyes |
| CiteThisProduct | C-646(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-350) |
BIOLOGicalDescription
| AlternativeNames | 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1Hpyrazol-1-yl]benzoicacid |
| ResearchAreas | CellSignaling,Epigenetics |
| PubChemID | 1285940 |
| ScientificBackground | Potentandselectiveinhibitorofthehistoneacetyltransferasep300/CBP(Ki=400nM).Inducesapoptosisinprostatecancercells.Enhancesfearextinctionmemoryandsynapticplasticityinmice.Promotestaudeacetylationreducinglevelsofpathogenicp-tau.Cellpermeable. |
| References | 1.BowersE.M.,etal.(2010)Chem.Biol.17:471. 2.SanterF.R.,etal.(2011)Mol.CancerTher.10:1644. 3.MarekR.,etal.(2011)J.Neurosci.31:7486. 4.MinS.W.,etal.(2010)Neuron67:953. |
ProductImages
ChemicalstructureofC-646(SIH-350),aHATinhibitor.CAS#:328968-36-1.MolecularFormula:C24H19N3O6.MolecularWeight:445.4g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
