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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/C-646/SIH-350-5MG/5-mg
商品详细StressMarq/C-646/SIH-350-5MG/5-mg
StressMarq/C-646/SIH-350-5MG/5-mg
StressMarq/C-646/SIH-350-5MG/5-mg
商品编号: SIH-350-5MG
市场价: ¥2020.00
美元价: 1212.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameC-646
Description

HATinhibitor

Purity>98%(TLC);NMR(Conforms)
CASNo.328968-36-1
MolecularFormulaC24H19N3O6
MolecularWeight445.4

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolublein10mg/mlDMSO
SourceSynthetic
AppearanceOrangeSolid
SMILESCC1=CC(=C(C=C1C)[N+](=O)[O-])C2=CC=C(O2)/C=C/3C(=NN(C3=O)C4=CC=C(C=C4)C(=O)O)C
InChIInChI=1S/C24H19N3O6/c1-13-10-20(21(27(31)32)11-14(13)2)22-9-8-18(33-22)12-19-15(3)25-26(23(19)28)17-6-4-16(5-7-17)24(29)30/h4-12H,1-3H3,(H,29,30)/b19-12+
InChIKeyHEKJYZZSCQBJGB-XDHOZWIPSA-N
SafetyPhrasesClassification:Caution–Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-Avoidcontactwithskinandeyes
CiteThisProductC-646(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-350)

BIOLOGicalDescription

AlternativeNames4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1Hpyrazol-1-yl]benzoicacid
ResearchAreasCellSignaling,Epigenetics
PubChemID1285940
ScientificBackgroundPotentandselectiveinhibitorofthehistoneacetyltransferasep300/CBP(Ki=400nM).Inducesapoptosisinprostatecancercells.Enhancesfearextinctionmemoryandsynapticplasticityinmice.Promotestaudeacetylationreducinglevelsofpathogenicp-tau.Cellpermeable.
References1.BowersE.M.,etal.(2010)Chem.Biol.17:471.
2.SanterF.R.,etal.(2011)Mol.CancerTher.10:1644.
3.MarekR.,etal.(2011)J.Neurosci.31:7486.
4.MinS.W.,etal.(2010)Neuron67:953.

ProductImages

<p>Chemical structure of C-646 (SIH-350), a HAT inhibitor. CAS #: 328968-36-1. Molecular Formula: C24H19N3O6. Molecular Weight: 445.4 g/mol.</p>

ChemicalstructureofC-646(SIH-350),aHATinhibitor.CAS#:328968-36-1.MolecularFormula:C24H19N3O6.MolecularWeight:445.4g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。