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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-BTK Antibody (pTyr223 + pTyr225)/SPC-928D/100-µl
商品详细StressMarq/Anti-BTK Antibody (pTyr223 + pTyr225)/SPC-928D/100-µl
StressMarq/Anti-BTK Antibody (pTyr223 + pTyr225)/SPC-928D/100-µl
StressMarq/Anti-BTK Antibody (pTyr223 + pTyr225)/SPC-928D/100-µl
商品编号: SPC-928D
市场价: ¥5900.00
美元价: 3540.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameBTKAntibody(pTyr223+pTyr225)
Description

RabbitAnti-HumanBTK(pTyr223+pTyr225)Polyclonal

SpeciesReactivityHuman
ApplicationsWB,AM
AntibodyDilutionWB(1:1000);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenAphospho-specificpeptidecorrespondingtoresiduessurroundingTyr223andTyr225ofhumanBTK(AA220-226)
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,0.025%Thimerosal
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationPeptideAffinityPurified
ClonalityPolyclonal
SpecificityDetects76.281kDa.
CiteThisProductStressMarqBiosciencesCat#SPC-928,RRID:AB_2707103
CertificateofAnalysisA1:250dilutionofSPC-928wassufficientfordetectionofBTK(pTyr223+pTyr225)in10µgofHEK293celllysatebyECLimmunoblotanalysisusinggoatanti-rabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesAgammaglobulinaemiatyrosinekinaseAntibody,AGMX1Antibody,ATKAntibody,BcellProgenitorkinaseAntibody,BrutontyrosinekinaseAntibody,IMD1Antibody,PSCTK1Antibody,TyrosineproteinkinaseBTKAntibody
ResearchAreasCellSignaling,Immunology,InnateImmunity,ProteinPhosphorylation,TLRSignaling,TyrosineKinases
CellularLocalizationCytoplasm,Membrane,Nucleus
AccessionNumberNP_000052
GeneID695
SwissProtQ06187
ScientificBackgroundBTKisacytoplasmicprotein-tyrosinekinase,involvedinBcelldevelopment,differentiationandsignalling.ItisadownstreamtargetoftheB-cellreceptorandplaysanimportantroleinimmunecellrelatedpathways.BTKhasadualfunctioninapoptosis.NotreportedtodirectlyinteractwithDNA.ExpressionofatruncatedBTKvariantinleukemia,whichmediatesphosphorylationandactivationofnormalBTKbyBCR-ABL1.ConstitutivelyactivatedBTKpromotescellsurvival.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。