StressMarq/BRL-50481/SIH-374-10MG/10-mg
商品编号：
SIH-374-10MG
市场价：
¥1440.00
美元价：
864.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| Product Name | BRL-50481 |
| Description | PDE7 inhibitor |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 433695-36-4 |
| Molecular Formula | C9H12N2O4S |
| Molecular Weight | 244.26 |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | May be dissolved in DMSO (40 mg/ml) or Ethanol (5 mg/ml) |
| Source | Synthetic |
| Appearance | Cream solid |
| SMILES | CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N(C)C |
| InChI | InChI=1S/C9H12N2O4S/c1-7-4-5-8(11(12)13)6-9(7)16(14,15)10(2)3/h4-6H,1-3H3 |
| InChIKey | IFIUFCJFLGCQPH-UHFFFAOYSA-N |
| Safety Phrases | Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection |
| Cite This Product | BRL-50481 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-374) |
Biological Description
| Alternative Names | N,N,2-Trimethyl-5-nitro-benzenesulfonamide |
| Research Areas | Neuroscience |
| PubChem ID | 2921148 |
| Scientific Background | BRL-50481 is a selective phosphodiesterase 7 (PDE7) inhibitor. In the presence of BRL-50481 the activity of hrPDE7A1 was inhibited against the phosphodiesterase (PDE3) and (PDE4) (1). Studies have suggested a potential role of BRL-50481 in the treatment of osteoporosis (2). |
| References |
1. Smith J., et al. (2004) Molecular Biology Pharmacology. 66(6): 1679-89. 2. Pekkinen M., et al. (2008) Bone. 43(1): 84-91. |
Product Images
Chemical structure of BRL-50481 (SIH-374), a PDE7 inhibitor. CAS #: 433695-36-4. Molecular Formula: C9H12N2O4S. Molecular Weight: 244.26 g/mol.
Product Citations (0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
