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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Bortezomib/SIH-328-25MG/25-mg
商品详细StressMarq/Bortezomib/SIH-328-25MG/25-mg
StressMarq/Bortezomib/SIH-328-25MG/25-mg
StressMarq/Bortezomib/SIH-328-25MG/25-mg
商品编号: SIH-328-25MG
市场价: ¥1700.00
美元价: 1020.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameBortezomib
Description

Proteasomeinhibitor

Purity>98%
CASNo.179324-69-7
MolecularFormulaC19H25BN4O4
MolecularWeight384.2

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolublein50mg/mlDMSO,35mg/mlEthanol
SourceSynthetic
AppearanceWhitePowder
SMILESB([[email protected]](CC(C)C)NC(=O)[[email protected]](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
InChIInChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h4-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1
InChIKeyGXJABQQUPOEUTA-RDJZCZTQSA-N
SafetyPhrasesClassification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-Avoidcontactwithskinandeyes
CiteThisProductBortezomib(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-328)

BIOLOGicalDescription

AlternativeNamesB-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronicAcid;[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronicAcid;Velcade;RADIciol;NSC681239;DPBA;LDP341;MG341;mlN341;NSC681239;PS314;PS341;Radiciol;Velcade
ResearchAreasCancer,Apoptosis,CancerGrowthInhibitors,ProteasomeInhibitors
PubChemID387447
ScientificBackgroundPotentandselectiveproteasomeinhibitor(Ki=0.6nM).Inhibitsproliferationofanumberoftumorcelllines(IC50=7nM).InhibitsTNFsynthesisandFGF-inducedangiogenesis.ReversIBLe.Cellpermeable.
References1.AdamsJ.,etal.(1999)CancerRes.59:2615.
2.WilliamsS.,etal.(2003)Mol.CancerTher.2:835.

ProductImages

<p>Chemical structure of Bortezomib (SIH-328), a Proteasome inhibitor. CAS #: 179324-69-7. Molecular Formula: C19H25BN4O4. Molecular Weight: 384.2 g/mol.</p>

ChemicalstructureofBortezomib(SIH-328),aProteasomeinhibitor.CAS#:179324-69-7.MolecularFormula:C19H25BN4O4.MolecularWeight:384.2g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。