StressMarq/Bortezomib/SIH-328-5MG/5-mg
商品编号：
SIH-328-5MG
市场价：
¥900.00
美元价：
540.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Bortezomib |
| Description | Proteasomeinhibitor |
| Purity | >98% |
| CASNo. | 179324-69-7 |
| MolecularFormula | C19H25BN4O4 |
| MolecularWeight | 384.2 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solublein50mg/mlDMSO,35mg/mlEthanol |
| Source | Synthetic |
| Appearance | WhitePowder |
| SMILES | B([[email protected]](CC(C)C)NC(=O)[[email protected]](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O |
| InChI | InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h4-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1 |
| InChIKey | GXJABQQUPOEUTA-RDJZCZTQSA-N |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-Avoidcontactwithskinandeyes |
| CiteThisProduct | Bortezomib(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-328) |
BIOLOGicalDescription
| AlternativeNames | B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronicAcid;[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronicAcid;Velcade;RADIciol;NSC681239;DPBA;LDP341;MG341;mlN341;NSC681239;PS314;PS341;Radiciol;Velcade |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,ProteasomeInhibitors |
| PubChemID | 387447 |
| ScientificBackground | Potentandselectiveproteasomeinhibitor(Ki=0.6nM).Inhibitsproliferationofanumberoftumorcelllines(IC50=7nM).InhibitsTNFsynthesisandFGF-inducedangiogenesis.ReversIBLe.Cellpermeable. |
| References | 1.AdamsJ.,etal.(1999)CancerRes.59:2615. 2.WilliamsS.,etal.(2003)Mol.CancerTher.2:835. |
ProductImages
ChemicalstructureofBortezomib(SIH-328),aProteasomeinhibitor.CAS#:179324-69-7.MolecularFormula:C19H25BN4O4.MolecularWeight:384.2g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
